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利用资源高效分层人口加权抽样调查方案估算人群肺癌风险——来自爱尔兰的经验和结果。

Estimating population lung cancer risk from radon using a resource efficient stratified population weighted sample survey protocol - Lessons and results from Ireland.

机构信息

School of Mathematics and Statistics, University College Dublin, Belfield, Dublin 4, Ireland.

Environmental Protection Agency, McCumiskey House, Richview, Clonskeagh, Dublin 14, Ireland.

出版信息

J Environ Radioact. 2021 Jul;233:106582. doi: 10.1016/j.jenvrad.2021.106582. Epub 2021 Apr 10.

DOI:10.1016/j.jenvrad.2021.106582
PMID:33848713
Abstract

A 2018 estimate indicates that there were 226,057 radon-attributable lung cancer deaths in 66 countries that had representative radon surveys. This is a shocking figure, and as it comes from only 66 countries it underestimates the worldwide death toll. Any research that enables countries to conduct representative radon surveys and to understand better the risk to citizens from radon is surely welcome. We hope this paper provides a useful methodology for estimating population risk. The estimation of population weighted average indoor radon levels requires statistically valid sampling methodologies that use a representative sample of occupied homes throughout the country. A literature review indicates that in many population weighted surveys, the sampling methodology may not have been designed to do this. This paper describes a simple, resource efficient methodology which produces statistically valid and reliable estimates based on a small scale sample that is representative of the population distribution. The resource efficient design of this study enables it to be repeated at frequent intervals providing for a longitudinal analysis of the population risk from indoor radon. This survey was conducted in Ireland using 653 measurements and a representative sampling strategy to provide a baseline population weighted radon exposure for future comparisons. This study estimates the average population weighted indoor radon concentration in Ireland to be 97.83 Bq m (95% Confidence Interval 90.69 Bq m to 105.53 Bq m), and that there are an estimated 350 lung cancer cases and 255 deaths per year due to radon exposure. The mortality rate of 5.3 per 100,000 due to indoor radon, demonstrates that radon remains one of the highest preventable causes of death in Ireland.

摘要

2018 年的一项估计表明,在开展过有代表性氡普查的 66 个国家中,有 226057 例肺癌死亡归因于氡。这是一个惊人的数字,而且由于它只来自 66 个国家,因此低估了全球的死亡人数。任何能够使各国开展有代表性的氡普查并更好地了解氡对公民风险的研究肯定都是受欢迎的。我们希望本文提供了一种有用的方法来估计人群风险。估计人群加权平均室内氡水平需要使用统计上有效的抽样方法,该方法利用全国范围内有代表性的居住房屋样本。文献综述表明,在许多人群加权调查中,抽样方法可能并未设计为做到这一点。本文描述了一种简单、资源高效的方法,该方法基于具有代表性的人口分布的小规模样本,可产生具有统计意义的可靠估计。本研究的资源高效设计使其能够频繁重复进行,从而对人群室内氡风险进行纵向分析。这项调查是在爱尔兰进行的,使用了 653 次测量和具有代表性的抽样策略,为未来的比较提供了人群加权氡暴露的基线。本研究估计爱尔兰人群加权室内氡平均浓度为 97.83 Bq m(95%置信区间为 90.69 Bq m 至 105.53 Bq m),估计每年有 350 例肺癌病例和 255 例死亡归因于氡暴露。由于室内氡导致的死亡率为 5.3/100,000,表明氡仍然是爱尔兰最高可预防死因之一。

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