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良性前列腺增生所致男性下尿路症状的机械性和消融性微创技术:根据 BPH-6 评估的系统评价。

Mechanical and Ablative Minimally Invasive Techniques for Male LUTS due to Benign Prostatic Obstruction: A Systematic Review according to BPH-6 Evaluation.

机构信息

Department of Urology, Magna Graecia University of Catanzaro, Catanzaro, Italy.

Department of Urology, University of Catania, Catania, Italy.

出版信息

Urol Int. 2021;105(9-10):858-868. doi: 10.1159/000514438. Epub 2021 Apr 13.

Abstract

The treatment of male lower urinary tract symptoms (LUTS) due to benign prostatic obstruction represents one of the major interesting aspects in urological clinical practice. Although transurethral resection of the prostate is still considered the surgical gold standard for treatment of benign prostatic hyperplasia with prostate volume <80 mL, various minimally invasive surgical treatments (MITs) have been developed to overcome the limitations of the "conventional" surgery. To date, there are no validated tools to evaluate the surgical outcomes of MITs; however, in the past, BPH-6 has been used for this purpose. In this systematic review, we evaluated the efficacy and safety of MITs according to BPH-6 score system. We focused our attention on MITs based on mechanical devices (prostatic urethral lift and the temporary implantable nitinol device) and techniques for prostate ablation (image guided robotic waterjet ablation and convective water vapor energy ablation). Evidence shows that MITs are capable of leading to an improvement in LUTS without having an overwhelming impact on complications and are a valid alternative to other treatments in patients who wish to preserve their sexual function or in case of inapplicability of conventional surgery. However, comparative studies between these techniques are still missing.

摘要

男性下尿路症状(LUTS)的治疗由于良性前列腺梗阻是泌尿科临床实践中一个主要的有趣方面。尽管经尿道前列腺切除术仍然被认为是治疗前列腺体积<80 毫升的良性前列腺增生的手术金标准,但已经开发了各种微创外科治疗(MITs)来克服“常规”手术的局限性。到目前为止,还没有经过验证的工具来评估 MITs 的手术效果;然而,在过去,BPH-6 曾被用于此目的。在本系统评价中,我们根据 BPH-6 评分系统评估了 MITs 的疗效和安全性。我们关注的是基于机械装置(前列腺尿道提升和临时可植入镍钛诺装置)和前列腺消融技术(图像引导机器人水射流消融和对流水蒸汽能量消融)的 MITs。有证据表明,MITs 能够改善 LUTS,而不会对并发症产生压倒性的影响,并且对于希望保留性功能的患者或在常规手术不适用的情况下,是其他治疗方法的有效替代。然而,这些技术之间的比较研究仍然缺乏。

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