Sessa Francesco, Polverino Paolo, Siena Giampaolo, Bisegna Claudio, Lo Re Mattia, Spatafora Pietro, Pecoraro Alessio, Rivetti Anna, Moscardi Luisa, Saladino Marco, Cocci Andrea, Gacci Mauro, Li Marzi Vincenzo, Carini Marco, Minervini Andrea, Campi Riccardo, Serni Sergio
Unit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, 50100 Florence, Italy.
Department of Experimental and Clinical Medicine, University of Florence, 50100 Florence, Italy.
J Clin Med. 2023 Jan 19;12(3):793. doi: 10.3390/jcm12030793.
We aimed to review the current evidence on surgical and functional outcomes of Transperineal Laser Ablation for LUTS due to BPH. A comprehensive review of the English-language literature was performed using the MEDLINE and Web of Science databases until 1 August 2022, aiming to select studies evaluating TPLA for the treatment of LUTS due to BPH. Additional records were found from Google Scholar. Data were extracted and summarized in Tables. An appropriate form was used for qualitative data synthesis. Seven studies were included in the review, with all being single arm, non-comparative studies. In all studies, functional outcomes were evaluated with uroflowmetry parameters and validated questionnaires, showing a promising effectiveness at short- and mid-term follow-up. There is a lack of standardized pathways for preoperative assessment of patients suitable for TPLA, and even the technique itself has been reported with a few nuances. A good safety profile has been reported by all the authors. Although promising results have been reported by different groups, selection criteria for TPLA and few technical nuances regarding the procedure were found to be heterogeneous across the published series that should be standardized in the future. Further research is needed to confirm these findings.
我们旨在回顾目前关于经会阴激光消融术治疗良性前列腺增生所致下尿路症状的手术及功能结局的证据。使用MEDLINE和Web of Science数据库对截至2022年8月1日的英文文献进行了全面回顾，旨在筛选评估经会阴激光消融术治疗良性前列腺增生所致下尿路症状的研究。通过谷歌学术搜索获取了更多记录。数据被提取并汇总在表格中。采用适当的形式进行定性数据综合分析。该综述纳入了7项研究，均为单臂非对照研究。在所有研究中，通过尿流率参数和经过验证的问卷对功能结局进行评估，结果显示在短期和中期随访中具有良好的疗效。对于适合经会阴激光消融术的患者，缺乏标准化的术前评估途径，甚至该技术本身也存在一些细微差异。所有作者均报告该手术具有良好的安全性。尽管不同研究小组均报告了有前景的结果，但经会阴激光消融术的选择标准以及该手术的一些技术细微差异在已发表的系列研究中存在异质性，未来应予以标准化。需要进一步的研究来证实这些发现。
