一名患有多个环形强化病灶的HIV患者原发性中枢神经系统淋巴瘤的诊断
Diagnosis of primary CNS lymphoma in a HIV patient with multiple ring-enhancing lesions.
作者信息
Patel Nishant, Charate Rishi
机构信息
Department of Internal Medicine, University of Louisville, Louisville, KY, USA.
出版信息
IDCases. 2021 Mar 10;24:e01065. doi: 10.1016/j.idcr.2021.e01065. eCollection 2021.
Abstract
Multiple ring-enhancing lesions on brain MRI in an immunocompromised patient are frequently associated with opportunistic infections such as toxoplasmosis. In this report, we describe the case of a patient with HIV/AIDS who was found to having multiple ring-enhancing lesions and was diagnosed with a primary central nervous system lymphoma.
摘要
免疫功能低下患者脑部磁共振成像（MRI）上出现的多发环形强化病灶常与机会性感染相关，如弓形虫病。在本报告中，我们描述了一例人类免疫缺陷病毒（HIV）/获得性免疫缺陷综合征（AIDS）患者，该患者被发现有多发环形强化病灶，并被诊断为原发性中枢神经系统淋巴瘤。
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本文引用的文献
1
HIV patients developing primary CNS lymphoma lack EBV-specific CD4+ T cell function irrespective of absolute CD4+ T cell counts.
PLoS Med. 2007 Mar 27;4(3):e96. doi: 10.1371/journal.pmed.0040096.
2
Management of HIV-associated focal brain lesions in developing countries.
QJM. 2004 Jul;97(7):413-21. doi: 10.1093/qjmed/hch080.
3
Changes in AIDS-related lymphoma since the era of highly active antiretroviral therapy.
Blood. 2001 Oct 15;98(8):2339-44. doi: 10.1182/blood.v98.8.2339.
4
Therapeutic management of primary central nervous system lymphoma: lessons from prospective trials.
Ann Oncol. 2000 Aug;11(8):927-37. doi: 10.1023/a:1008376412784.
5
Primary intracranial neoplasms in patients with HIV.
Neurology. 1999 May 12;52(8):1648-51. doi: 10.1212/wnl.52.8.1648.
6
Characterization of primary intracranial lymphoma by computed tomography: an analysis of 36 cases and a review of the literature with particular reference to calcification haemorrhage and cyst formation.
Clin Radiol. 1998 Jun;53(6):428-34. doi: 10.1016/s0009-9260(98)80271-7.
7
Non-Hodgkin's lymphoma among people with AIDS: incidence, presentation and public health burden. AIDS/Cancer Study Group.
Int J Cancer. 1997 Nov 27;73(5):645-50. doi: 10.1002/(sici)1097-0215(19971127)73:5<645::aid-ijc6>3.0.co;2-x.
8
CNS involvement in AIDS: spectrum of CT and MR findings.
Eur Radiol. 1997;7(7):1091-7. doi: 10.1007/s003300050260.
9
The variable MR appearance of primary lymphoma of the central nervous system: comparison with histopathologic features.
AJNR Am J Neuroradiol. 1997 Mar;18(3):563-72.
10
Primary central nervous system lymphomas: natural history and response to radiation therapy in 55 patients with acquired immunodeficiency syndrome.
J Neurosurg. 1990 Aug;73(2):206-11. doi: 10.3171/jns.1990.73.2.0206.
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