University of Portsmouth, Portsmouth, United Kingdom.
Department of Environmental Science, Stockholm University, Stockholm, Sweden.
Environ Sci Technol. 2021 May 4;55(9):5620-5628. doi: 10.1021/acs.est.0c06493. Epub 2021 Apr 14.
For decades, we have known that chemicals affect human and wildlife behavior. Moreover, due to recent technological and computational advances, scientists are now increasingly aware that a wide variety of contaminants and other environmental stressors adversely affect organismal behavior and subsequent ecological outcomes in terrestrial and aquatic ecosystems. There is also a groundswell of concern that regulatory ecotoxicology does not adequately consider behavior, primarily due to a lack of standardized toxicity methods. This has, in turn, led to the exclusion of many behavioral ecotoxicology studies from chemical risk assessments. To improve understanding of the challenges and opportunities for behavioral ecotoxicology within regulatory toxicology/risk assessment, a unique workshop with international representatives from the fields of behavioral ecology, ecotoxicology, regulatory (eco)toxicology, neurotoxicology, test standardization, and risk assessment resulted in the formation of consensus perspectives and recommendations, which promise to serve as a roadmap to advance interfaces among the basic and translational sciences, and regulatory practices.
几十年来，我们已经知道化学物质会影响人类和野生动物的行为。此外，由于最近技术和计算方面的进步，科学家们现在越来越意识到，各种各样的污染物和其他环境胁迫因素会对陆地和水生生态系统中的生物行为和随后的生态结果产生不利影响。人们也越来越担心，监管毒理学没有充分考虑行为，主要是因为缺乏标准化的毒性方法。这反过来又导致许多行为毒理学研究被排除在化学风险评估之外。为了提高对行为毒理学在监管毒理学/风险评估中的挑战和机遇的理解，一个具有国际代表性的行为生态学、生态毒理学、监管（生态）毒理学、神经毒理学、测试标准化和风险评估领域的独特研讨会促成了共识观点和建议的形成，有望成为推进基础和转化科学以及监管实践之间接口的路线图。
