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临床药师干预对痴呆症治疗依从性和照顾者知识的影响。

Effect of clinical pharmacists' interventions on dementia treatment adherence and caregivers' knowledge.

机构信息

Department of Clinical Pharmacy, Hacettepe University Faculty of Pharmacy, Ankara, Turkey.

Department of Internal Medicine, Division of Geriatric Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey.

出版信息

Geriatr Gerontol Int. 2021 Jun;21(6):506-511. doi: 10.1111/ggi.14170. Epub 2021 Apr 14.

Abstract

AIM

Poor adherence with dementia medications is common among patients and caregivers, owing to the absence of perceived effect, polypharmacy, and adverse effects. The aim of this study was to evaluate the effect of clinical pharmacists' interventions on the adherence to dementia treatment and the caregivers' knowledge of dementia.

METHODS

This study was conducted at a geriatric outpatient clinic of the university hospital between October 2018 and April 2019. The Morisky Green Levine Adherence Scale (MGLS) to patients or caregivers and the Dementia Knowledge Assessment Tool Version Two (DKAT2) to caregivers were applied at the beginning of the study and 4 months later by a clinical pharmacist. After the scales were applied in the first interview, verbal information about the importance of adherence to dementia treatment, and incorrect answers of caregivers in DKAT2 were provided by the clinical pharmacist.

RESULTS

A total of 94 patients and 91 caregivers were included in the study. High adherence to treatment was determined in 70.2% of the patients in the first interview and in 95.7% in the second interview (P < 0.001). The mean score of DKAT2 was 15.53 ± 2.44 in the first interview, while the median score of DKAT2 in the second interview was 19.11 ± 1.25 (P < 0.001).

CONCLUSION

The intervention of clinical pharmacists significantly increased the adherence to dementia treatment and the caregivers' knowledge of dementia. Close monitoring of dementia patients and caregivers by clinical pharmacists and collaboration with a multidisciplinary team play an important role in dementia care. Geriatr Gerontol Int 2021; 21: 506-511.

摘要

目的

由于缺乏感知效果、多种药物治疗和不良反应,痴呆患者及其照护者经常不遵医嘱用药。本研究旨在评估临床药师干预对痴呆治疗依从性和照护者痴呆知识的影响。

方法

本研究于 2018 年 10 月至 2019 年 4 月在大学医院老年门诊进行。在研究开始时和 4 个月后,临床药师分别通过 Morisky Green Levine 依从性量表(MGLS)对患者或照护者和痴呆知识评估工具第二版(DKAT2)对照护者进行评估。在第一次访谈中应用量表后,临床药师会向照护者提供有关痴呆治疗依从性重要性的口头信息和 DKAT2 中照护者的错误答案。

结果

本研究共纳入 94 名患者和 91 名照护者。在第一次访谈中,70.2%的患者被确定为高度遵医嘱用药,而在第二次访谈中,95.7%的患者为高度遵医嘱用药(P<0.001)。第一次访谈中 DKAT2 的平均得分为 15.53±2.44,而第二次访谈中 DKAT2 的中位数得分为 19.11±1.25(P<0.001)。

结论

临床药师的干预显著提高了痴呆患者的治疗依从性和照护者的痴呆知识。临床药师密切监测痴呆患者及其照护者,并与多学科团队合作,对痴呆护理具有重要作用。老年医学与老年病学杂志 2021;21:506-511.

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