School of Medical and Surgical Sciences, University of Nottingham, Nottingham, UK.
Plastics Department, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Ann R Coll Surg Engl. 2021 Oct;103(9):e272-e274. doi: 10.1308/rcsann.2020.7145. Epub 2021 Apr 14.
We discuss the unusual repigmentation of a vitiliginous region of a nipple areolar complex following a therapeutic mammoplasty. We consider the autoimmune mechanisms behind the pathogenesis of vitiligo and their potential interplay with the immunological pathways involved in this patient's breast cancer and ultimately in the postoperative recovery period. This case highlights the potential interconnecting thread of immunological disruptions, which may provide a springboard for further discussion around the treatment for vitiligo. It also provides a useful point of note when counselling darker skin patients around scarring when undergoing surgical interventions.
我们讨论了一例乳房成形术后乳头乳晕复合体的白癜风区域出现异常复色现象。我们考虑了白癜风发病机制背后的自身免疫机制及其与该患者乳腺癌相关的免疫途径的潜在相互作用,并最终影响术后恢复期。本病例突出了免疫紊乱的潜在关联,这可能为进一步讨论白癜风的治疗提供了一个起点。在对接受手术干预的深色皮肤患者进行瘢痕咨询时,这也是一个有用的注意点。