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治疗性乳房成形术后乳晕复合体部分复色。

Partial repigmentation of a vitiliginous nipple areolar complex following therapeutic mammoplasty.

机构信息

School of Medical and Surgical Sciences, University of Nottingham, Nottingham, UK.

Plastics Department, Nottingham University Hospitals NHS Trust, Nottingham, UK.

出版信息

Ann R Coll Surg Engl. 2021 Oct;103(9):e272-e274. doi: 10.1308/rcsann.2020.7145. Epub 2021 Apr 14.

DOI:10.1308/rcsann.2020.7145
PMID:33851889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10335233/
Abstract

We discuss the unusual repigmentation of a vitiliginous region of a nipple areolar complex following a therapeutic mammoplasty. We consider the autoimmune mechanisms behind the pathogenesis of vitiligo and their potential interplay with the immunological pathways involved in this patient's breast cancer and ultimately in the postoperative recovery period. This case highlights the potential interconnecting thread of immunological disruptions, which may provide a springboard for further discussion around the treatment for vitiligo. It also provides a useful point of note when counselling darker skin patients around scarring when undergoing surgical interventions.

摘要

我们讨论了一例乳房成形术后乳头乳晕复合体的白癜风区域出现异常复色现象。我们考虑了白癜风发病机制背后的自身免疫机制及其与该患者乳腺癌相关的免疫途径的潜在相互作用,并最终影响术后恢复期。本病例突出了免疫紊乱的潜在关联,这可能为进一步讨论白癜风的治疗提供了一个起点。在对接受手术干预的深色皮肤患者进行瘢痕咨询时,这也是一个有用的注意点。

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本文引用的文献

1
Markedly Reduced Risk of Internal Malignancies in Patients With Vitiligo: A Nationwide Population-Based Cohort Study.白癜风患者发生内部恶性肿瘤的风险显著降低:一项全国范围内基于人群的队列研究。
J Clin Oncol. 2019 Apr 10;37(11):903-911. doi: 10.1200/JCO.18.01223. Epub 2019 Feb 20.
2
New discoveries in the pathogenesis and classification of vitiligo.白癜风发病机制和分类的新发现。
J Am Acad Dermatol. 2017 Jul;77(1):1-13. doi: 10.1016/j.jaad.2016.10.048.
3
New insights into immune mechanisms of vitiligo.白癜风免疫机制的新见解。
G Ital Dermatol Venereol. 2016 Feb;151(1):44-54. Epub 2015 Oct 29.
4
The immune response to surgery and infection.对手术和感染的免疫反应。
Cent Eur J Immunol. 2014;39(4):532-7. doi: 10.5114/ceji.2014.47741. Epub 2014 Dec 15.
5
Oncological and cosmetic outcomes of oncoplastic breast conserving surgery.肿瘤整形保乳手术的肿瘤学及美容效果
Eur J Surg Oncol. 2005 Oct;31(8):817-23. doi: 10.1016/j.ejso.2005.05.010.