受生物启发的钨键乙炔的亲核进攻：碳阳离子和烯基配合物的形成。

Institute of Chemistry, Inorganic Chemistry, University of Graz, 8010 Graz, Austria.

Inorg Chem. 2021 Jun 21;60(12):8414-8418. doi: 10.1021/acs.inorgchem.1c00643. Epub 2021 Apr 14.

Inspired by the proposed inner-sphere mechanism of the tungstoenzyme acetylene hydratase, we have designed tungsten acetylene complexes and investigated their reactivity. Here, we report the first intermolecular nucleophilic attack on a tungsten-bound acetylene (CH) in bioinspired complexes employing 6-methylpyridine-2-thiolate ligands. By using PMe as a nucleophile, we isolated cationic carbyne and alkenyl complexes.

受钨酶乙炔水合酶提出的内球机理的启发，我们设计了钨乙炔配合物并研究了它们的反应性。在这里，我们报告了首例生物启发配合物中钨键乙炔（CH）的分子间亲核进攻，采用 6-甲基吡啶-2-硫醇配体。通过使用 PMe 作为亲核试剂，我们分离出了阳离子碳化物和烯基配合物。