Institute of Health Policy and Management, National Taiwan University, Taipei, Taiwan.
Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Dou‑Liu City, Taiwan.
PLoS One. 2021 Apr 14;16(4):e0249750. doi: 10.1371/journal.pone.0249750. eCollection 2021.
We used nationwide population-based data to identify optimal hospital and surgeon volume thresholds and to discover the effects of these volume thresholds on operative mortality and length of stay (LOS) for coronary artery bypass surgery (CABG).
Retrospective cohort study.
General acute care hospitals throughout Taiwan.
A total of 12,892 CABG patients admitted between 2011 and 2015 were extracted from Taiwan National Health Insurance claims data.
Operative mortality and LOS. Restricted cubic splines were applied to discover the optimal hospital and surgeon volume thresholds needed to reduce operative mortality. Generalized estimating equation regression modeling, Cox proportional-hazards modeling and instrumental variables analysis were employed to examine the effects of hospital and surgeon volume thresholds on the operative mortality and LOS.
The volume thresholds for hospitals and surgeons were 55 cases and 5 cases per year, respectively. Patients who underwent CABG from hospitals that did not reach the volume threshold had higher operative mortality than those who received CABG from hospitals that did reach the volume threshold. Patients who underwent CABG with surgeons who did not reach the volume threshold had higher operative mortality and LOS than those who underwent CABG with surgeons who did reach the volume threshold.
This is the first study to identify the optimal hospital and surgeon volume thresholds for reducing operative mortality and LOS. This supports policies regionalizing CABG at high-volume hospitals. Identifying volume thresholds could help patients, providers, and policymakers provide optimal care.
我们利用全国性基于人群的数据,确定最佳医院和外科医生手术量阈值,并发现这些阈值对冠状动脉旁路移植术(CABG)的手术死亡率和住院时间(LOS)的影响。
回顾性队列研究。
台湾各地的综合急性护理医院。
从台湾全民健康保险理赔数据中提取了 2011 年至 2015 年间共 12892 例 CABG 患者。
手术死亡率和 LOS。应用限制立方样条法发现降低手术死亡率所需的最佳医院和外科医生手术量阈值。采用广义估计方程回归模型、Cox 比例风险模型和工具变量分析来检验医院和外科医生手术量阈值对手术死亡率和 LOS 的影响。
医院和外科医生的手术量阈值分别为 55 例和 5 例/年。在未达到手术量阈值的医院接受 CABG 的患者的手术死亡率高于在达到手术量阈值的医院接受 CABG 的患者。在未达到手术量阈值的外科医生处接受 CABG 的患者的手术死亡率和 LOS 均高于在达到手术量阈值的外科医生处接受 CABG 的患者。
这是第一项确定降低手术死亡率和 LOS 的最佳医院和外科医生手术量阈值的研究。这支持将 CABG 集中在高容量医院的政策。确定手术量阈值可以帮助患者、提供者和政策制定者提供最佳护理。