Discipline of Psychiatry, Adelaide Medical School, University of Adelaide, Adelaide, Australia.
Department of Psychiatry, School of Medicine, University of Occupational and Environmental Health, Kitakyushu City, Japan.
Psychiatry Res. 2021 Jun;300:113906. doi: 10.1016/j.psychres.2021.113906. Epub 2021 Apr 3.
Cognitive and emotional remediation training for depression (CERT-D): a randomised controlled trial to improve cognitive, emotional and functional outcomes in depression The aim of the current study was to evaluate an experimental treatment designed to improve psychosocial function in patients with Major Depressive Disorder (MDD) by reinforcing cognitive, emotional, and social-cognitive abilities. Participants (N = 112) with current or lifetime MDD were recruited to participate in a randomised, blinded, controlled trial. Exclusion criteria included diagnosis of a substance abuse disorder, bipolar disorder organic, eating disorders, or illness which affect cognitive function. The treatment involved repeated cognitive training designed to improve cognitive, emotional, and social-cognitive abilities. In training sessions, the principles of cognitive training were applied across cognitive, emotional, and social domains, with participants completing repeated mental exercises. Exercises included critically analysing interpretations of social interactions (e.g., body language), exploring emotional reactions to stimuli, and completing game-like cognitive training tasks. Training sessions placed great emphasis on the application of trained cognitive, emotional, and social cognitive skills to psychosocial outcomes. Outcomes demonstrated significant improvement in psychosocial function, symptom severity, self-reported cognition, and social-cognition. Our findings demonstrate the efficacy of multi-domain cognitive training to improve psychosocial functioning in individuals with MDD. We suggest that the present treatment could be deployed at a lower cost and with minimal training in comparison to established psychological therapies.
认知和情绪矫正训练治疗抑郁症（CERT-D）：改善抑郁症患者认知、情绪和功能结局的随机对照试验 本研究旨在评估一种旨在通过增强认知、情绪和社会认知能力来改善重性抑郁障碍（MDD）患者心理社会功能的实验性治疗。招募了当前或有过 MDD 病史的参与者（N=112）参加随机、盲法、对照试验。排除标准包括物质滥用障碍、双相情感障碍、器质性疾病、进食障碍或影响认知功能的疾病的诊断。治疗包括重复认知训练，旨在提高认知、情绪和社会认知能力。在训练课程中，认知训练的原则适用于认知、情绪和社会领域，参与者完成重复的心理练习。练习包括批判性地分析对社交互动（例如肢体语言）的解释、探索对刺激的情绪反应以及完成类似游戏的认知训练任务。训练课程非常重视将经过训练的认知、情绪和社会认知技能应用于心理社会结果。结果表明心理社会功能、症状严重程度、自我报告的认知和社会认知都有显著改善。我们的发现证明了多领域认知训练在改善 MDD 患者心理社会功能方面的有效性。我们认为，与既定的心理治疗相比，目前的治疗可以以更低的成本和最小的培训来实施。
