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建立腹膜透析置管患者早期和中期并发症的预测模型。

Establishment of a prediction model for early and mid-term complications for patients undergoing catheter insertion for peritoneal dialysis.

作者信息

Ma Yibo, Liu Shuiqing, Yang Min, Zou Yun, Xue Dong, Wang Yufeng, Xie Xiao, Chen Hui, Liu Yanping

机构信息

Department of Ultrasound, the Third Affiliated Hospital of Soochow University, Changzhou, China.

Department of Nephrology, the Third Affiliated Hospital of Soochow University, Changzhou, China.

出版信息

J Int Med Res. 2021 Apr;49(4):3000605211004524. doi: 10.1177/03000605211004524.

Abstract

OBJECTIVE

To investigate the factors involved in early and mid-term complications after catheter insertion for peritoneal dialysis and to establish prediction models.

METHODS

A total of 158 patients with peritoneal dialysis in the Department of Nephrology of our hospital were retrospectively analyzed. General information, laboratory indices, early complications (within 1 month after the operation), mid-term complications (1-6 months after the operation), and other relevant data were recorded. Multivariate logistic regression analysis was performed to establish a prediction model of complications and generate a nomogram. Receiver operating characteristic (ROC) curve analysis was used to evaluate the efficacy of the model.

RESULTS

Among the patients, 48 (30.8%) had early complications, which were mainly catheter-related complications, and 29 (18.4%) had mid-term complications, which were mainly abdominal infection and catheter migration. We constructed a prediction model for early complications (area under the curve = 0.697, 95% confidence interval: 0.609-0.785) and mid-term complications (area under the curve = 0.730, 95% confidence interval: 0.622-0.839). The sensitivity was 0.750 and 0.607, and the specificity was 0.589 and 0.765, respectively.

CONCLUSIONS

Our prediction model has clinical significance for risk assessment of early and mid-term complications and prevention of complications after catheterization for peritoneal dialysis.

摘要

目的

探讨腹膜透析置管术后早期和中期并发症的相关因素,并建立预测模型。

方法

回顾性分析我院肾内科158例腹膜透析患者。记录一般资料、实验室指标、早期并发症(术后1个月内)、中期并发症(术后1 - 6个月)及其他相关数据。采用多因素logistic回归分析建立并发症预测模型并生成列线图。采用受试者工作特征(ROC)曲线分析评估模型的效能。

结果

患者中,48例(30.8%)发生早期并发症,主要为导管相关并发症;29例(18.4%)发生中期并发症,主要为腹腔感染和导管移位。我们构建了早期并发症预测模型(曲线下面积 = 0.697,95%置信区间:0.609 - 0.785)和中期并发症预测模型(曲线下面积 = 0.730,95%置信区间:0.622 - 0.839)。敏感性分别为0.750和0.607,特异性分别为0.589和0.765。

结论

我们的预测模型对腹膜透析置管术后早期和中期并发症的风险评估及并发症预防具有临床意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6739/8059045/b7fd1e031eaf/10.1177_03000605211004524-fig1.jpg

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