National Research Centre for the Working Environment, Lersø Parkallé 105, 2100, Copenhagen, Denmark.
Department of Occupational and Social Medicine, Holbæk Hospital, a part of Copenhagen University Hospital, Gl. Ringstedvej 4B, 4300, Holbæk, Denmark.
BMC Public Health. 2021 Apr 14;21(1):721. doi: 10.1186/s12889-021-10651-w.
Heavy occupational lifting is prevalent in the general working population and is sparsely reported to associate with hypertension, especially among older and hypertensive workers. We investigated if heavy occupational lifting is associated with hypertension and blood pressure (BP) in both cross-sectional and prospective study designs in the Copenhagen General Population Study, stratified by age, and use of anti-hypertensives.
Participation was conducted following the declaration of Helsinki and approved by the ethical committee (H-KF-01-144/01). By multivariable logistic and linear regression models, we investigated the association between heavy occupational lifting and hypertension, in a cross-sectional design (n = 67,363), using anti-hypertensives or BP ≥140/≥90 mmHg as outcome, and in a prospective design (n = 7020) with an above-median change in systolic BP (SBP) from baseline to follow-up and/or a shift from no use to use of anti-hypertensives as outcome, with and without stratification by age and use of anti-hypertensives.
The odds ratio for hypertension was estimated at 0.97 (99% CI: 0.93-1.00) in the cross-sectional analysis, and at 1.08 (99% CI: 0.98-1.19) in the prospective analysis. The difference in SBP among workers with versus without heavy occupational lifting was estimated at - 0.29 mmHg (99% CI -0.82 - 0.25) in the cross-sectional and at 1.02 mmHg (99% CI -0.41 - 2.45) in the prospective analysis. No significant interaction between heavy occupational lifting and age, nor use of anti-hypertensives were shown.
Only the prospective analysis indicated heavy occupational lifting to increase the risk of hypertension. Further research on the association between occupational lifting and hypertension are needed.
重体力职业性举重在普通劳动人群中较为普遍，但很少有研究表明其与高血压相关，尤其是在年龄较大和患有高血压的劳动者中。我们通过哥本哈根普通人群研究的横断面和前瞻性研究设计，调查了重体力职业性举重与高血压及血压（BP）之间的关系，研究设计按年龄和抗高血压药物的使用情况进行分层。
本研究遵循赫尔辛基宣言进行，并经伦理委员会批准（H-KF-01-144/01）。我们通过多变量逻辑回归和线性回归模型，在横断面设计（n=67363）中，以使用抗高血压药物或 BP≥140/≥90mmHg 为结局，在前瞻性设计（n=7020）中，以收缩压（SBP）从基线到随访时的中位数以上变化和/或从不使用抗高血压药物转变为使用抗高血压药物为结局，调查了重体力职业性举重与高血压之间的关联，并按年龄和抗高血压药物的使用情况进行分层。
在横断面分析中，高血压的比值比估计为 0.97（99%CI：0.93-1.00），在前瞻性分析中为 1.08（99%CI：0.98-1.19）。有与无重体力职业性举重的劳动者之间的 SBP 差异估计值在横断面研究中为-0.29mmHg（99%CI：-0.82至-0.25），在前瞻性研究中为 1.02mmHg（99%CI：-0.41至 2.45）。未显示重体力职业性举重与年龄、抗高血压药物的使用之间存在显著交互作用。
只有前瞻性分析表明重体力职业性举重会增加患高血压的风险。需要进一步研究职业性举重与高血压之间的关系。
