肺腺癌伴异时性卵巢转移：一个长期生存病例报告。
Lung Adenocarcinoma with Metachronous Ovarian Metastasis: a long survival case report.
机构信息
Department of Thoracic Surgery, Xuanwu Hospital, The Capital Medical University, Beijing, China.
Department of Pathology, Xuanwu Hospital, The Capital Medical University, Beijing, China.
出版信息
BMC Womens Health. 2021 Apr 14;21(1):152. doi: 10.1186/s12905-021-01284-7.
BACKGROUND
Lung adenocarcinoma which invades ovaries is very rare. However, with the increase of long-survival female lung cancer, more patients will suffer ovarian metastasis. On grounds of the paucity of reported cases, the clinicopathological features and treatment strategies remain unknown.
CASE PRESENTATION
This patient was stage IV lung adenocarcinoma at first diagnosis. Following multiple-line systemic treatments, she experienced extensive pelvic metastasis. After debulking surgery and reevaluation about the drive genes, she was administered by targeted therapy. Up to now, the patient has shown no evidence of progression for 8 years after the initial diagnosis of primary lung cancer and 46 months after her ovarian metastasis.
CONCLUSION
The comprehensive treatment modality for the bilateral ovarian metastasis is effective in clinical course.
背景
肺癌累及卵巢非常罕见。然而，随着长期生存的女性肺癌患者的增加，更多的患者将发生卵巢转移。由于报道的病例较少，其临床病理特征和治疗策略仍不清楚。
病例介绍
该患者初诊时为 IV 期肺腺癌。经过多线系统治疗后，她出现广泛的盆腔转移。在进行减瘤手术和驱动基因评估后，她接受了靶向治疗。截至目前，该患者在原发性肺癌初诊后 8 年和卵巢转移后 46 个月时，无疾病进展证据。
结论
双侧卵巢转移的综合治疗模式在临床过程中是有效的。
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