Thoracic Surgery and Lung Transplant Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University Hospital of Padua, Padua, Italy.
Thoracic Surgery and Lung Transplant Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University Hospital of Padua, Padua, Italy.
Transplant Proc. 2021 May;53(4):1382-1384. doi: 10.1016/j.transproceed.2021.03.016. Epub 2021 Apr 11.
A recent history of malignancy is an absolute contraindication for lung transplantation according to the International Society of Heart and Lung Transplantation; however, a 5-year disease-free interval should be demonstrated in most cases of malignancies to consider the patient a suitable recipient. Currently, no specific guidelines are reported for addressing previous lung cancer in the selection of recipients. We report a case of a patient who underwent right upper lobectomy for small cell lung cancer in 2013 followed by adjuvant chemotherapy and prophylactic encephalic radiotherapy. In 2019 she underwent lung transplantation for emphysema. Currently she is alive with no recurrence of neoplastic disease.
根据国际心肺移植学会的规定，近期有恶性肿瘤病史是肺移植的绝对禁忌证；但大多数情况下，需要在恶性肿瘤治愈 5 年以上才考虑患者适合接受肺移植。目前，在选择受者时，还没有针对既往肺癌的具体指南。我们报告了 1 例患者，该患者于 2013 年因小细胞肺癌行右上肺叶切除术，随后行辅助化疗和预防性脑放疗。2019 年，她因肺气肿接受了肺移植。目前，患者无肿瘤疾病复发，存活。
