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局限期小细胞肺癌（SCLC）每日分割放疗的最佳时机：简要报告。

Optimal timing of thoracic radiotherapy in limited stage small cell lung cancer (SCLC) with daily fractionation: A brief report.

机构信息

Allegheny Health Network Cancer Institute, Division of Radiation Oncology, Pittsburgh.

Allegheny Health Network, Department of Internal Medicine, Pittsburgh.

出版信息

Radiother Oncol. 2019 Mar;132:23-26. doi: 10.1016/j.radonc.2018.11.005. Epub 2018 Dec 20.

DOI:10.1016/j.radonc.2018.11.005
PMID:30825965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7427834/
Abstract

Survival in limited stage small cell lung cancer (LS-SCLC) improves with faster initiation of hyper-fractionated thoracic radiotherapy (TRT) following chemotherapy, however, it is unknown if this association exists for more commonly employed daily fractionated regimens. Our results suggest that this association is present even with daily fractionation.

摘要

局限期小细胞肺癌（LS-SCLC）患者的生存率随着化疗后更快开始超分割胸部放射治疗（TRT）而提高，但是否与更常用的每日分割方案存在这种关联尚不清楚。我们的结果表明，即使采用每日分割，这种关联也存在。

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本文引用的文献

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Utilization of Hyperfractionated Radiation in Small-Cell Lung Cancer and Its Impact on Survival.超分割放射治疗在小细胞肺癌中的应用及其对生存的影响。
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Timing of chest radiotherapy in patients with limited stage small cell lung cancer: a systematic review and meta-analysis of randomised controlled trials.局限期小细胞肺癌患者胸部放疗的时机：随机对照试验的系统评价和荟萃分析
Cancer Treat Rev. 2007 Aug;33(5):461-73. doi: 10.1016/j.ctrv.2007.03.002. Epub 2007 May 21.
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Time between the first day of chemotherapy and the last day of chest radiation is the most important predictor of survival in limited-disease small-cell lung cancer.化疗第一天至胸部放疗最后一天之间的时间是局限期小细胞肺癌生存的最重要预测因素。
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Systematic review and meta-analysis of randomised, controlled trials of the timing of chest radiotherapy in patients with limited-stage, small-cell lung cancer.局限期小细胞肺癌患者胸部放疗时机的随机对照试验的系统评价和荟萃分析
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