Chao Chao-Chin, Mo Lein-Ray, Hu Susan C
Department of Gastroenterology, Kaohsiung Municipal Gangshan Hospital, Kaohsiung City 820, Taiwan.
Department of Gastroenterology, Tainan Municipal Hospital, Tainan City 701, Taiwan.
Biomed Res Int. 2021 Mar 27;2021:7605324. doi: 10.1155/2021/7605324. eCollection 2021.
Capsule endoscopy (CE) is a useful diagnostic modality for patients with occult gastrointestinal (GI) bleeding. However, most previous studies utilizing CE have focused on techniques, patient characteristics, safety and feasibility, and case analyses. Studies evaluating the optimal timing for utilizing CE, which is an essential factor for obtaining a better diagnostic yield, remain scarce in the literature. Considering that a CE examination is expensive, we, therefore, undertook this study to evaluate, analyze, and determine the optimal time for performing CE in patients with occult GI bleeding.
Seventy-five patients were initially recruited, but finally, sixty patients with significant GI bleeding with an unknown etiology after traditional endoscopic examinations were included in the study. All data were collected from a local hospital in Taiwan, encompassing the period from 2010 to 2018. The relationship between the timing of CE examination and the diagnostic correction rate (DCR) was then analyzed statistically.
More female (58.3%) and older adult (68.3%) patients were in our study. Based on the four analytical models used in the study, the results showed that the most optimal time to perform CE is within three days after GI bleeding occurs.
胶囊内镜检查（CE）对于隐匿性胃肠道（GI）出血患者是一种有用的诊断方式。然而，以往大多数使用CE的研究都集中在技术、患者特征、安全性和可行性以及病例分析上。评估使用CE的最佳时机（这是获得更高诊断率的关键因素）的研究在文献中仍然很少。鉴于CE检查费用昂贵，因此，我们开展了这项研究，以评估、分析并确定隐匿性GI出血患者进行CE检查的最佳时间。
最初招募了75名患者，但最终，60名在传统内镜检查后病因不明的严重GI出血患者被纳入研究。所有数据均收集自台湾一家当地医院，涵盖2010年至2018年期间。然后对CE检查时间与诊断校正率（DCR）之间的关系进行统计学分析。
我们的研究中女性患者（58.3%）和老年患者（68.3%）较多。基于该研究中使用的四种分析模型，结果表明进行CE的最佳时间是在GI出血发生后的三天内。
