局限性极低危、低危和中危前列腺癌治疗共识：来自发展中国家前列腺癌第一次共识会议的报告(PCCCDC)。
Consensus on Prostate Cancer Treatment of Localized Disease With Very Low, Low, and Intermediate Risk: A Report From the First Prostate Cancer Consensus Conference for Developing Countries (PCCCDC).
机构信息
Hospital Erasto Gaertner, Curitiba, Brazil.
A Beneficiência Portuguesa de São Paulo, São Paulo, Brazil.
出版信息
JCO Glob Oncol. 2021 Apr;7:523-529. doi: 10.1200/GO.20.00515.
PURPOSE
A group of international urology and medical oncology experts developed and completed a survey on prostate cancer (PCa) in developing countries. The results are reviewed and summarized, and recommendations on consensus statements for very low-, low-, and intermediate-risk PCa focused on developing countries were developed.
METHODS
A panel of experts developed more than 300 survey questions of which 66 questions concern the principal areas of interest of this paper: very low, low, and intermediate risk of PCa in developing countries. A larger panel of 99 international multidisciplinary cancer experts voted on these questions to create the recommendations for treatment and follow-up for very low-, low-, and intermediate-risk PCa in areas of limited resources discussed in this manuscript.
RESULTS
The panel voted publicly but anonymously on the predefined questions. Each question was deemed consensus if 75% or more of the full panel had selected a particular answer. These answers are based on panelist opinion not a literature review or meta-analysis. For questions that refer to an area of limited resources, the recommendations consider cost-effectiveness and the possible therapies with easier and greater access. Each question had five to seven relevant answers including two nonanswers. The results were tabulated in real time.
CONCLUSION
The voting results and recommendations presented in this document can be used by physicians to support management for very low, low, and intermediate risk of PCa in areas of limited resources. Individual clinical decision making should be supported by available data; however, as guidelines for treatment for very low, low, and intermediate risk of PCa in developing countries have not been developed, this document will serve as a point of reference when confronted with this disease.
目的
一组国际泌尿科和肿瘤医学专家制定并完成了一项针对发展中国家前列腺癌（PCa）的调查。现将结果进行回顾和总结，并就发展中国家极低危、低危和中危 PCa 的共识声明提出建议。
方法
专家组制定了 300 多个调查问题，其中 66 个问题涉及本文的主要关注领域：发展中国家极低危、低危和中危 PCa。一个由 99 名国际多学科癌症专家组成的更大的小组对这些问题进行了投票，以制定在本手稿中讨论的资源有限地区的极低危、低危和中危 PCa 的治疗和随访建议。
结果
专家组对预先定义的问题进行了公开但匿名投票。如果超过 75%的全体小组成员选择了特定的答案，则认为该问题达成共识。这些答案基于小组成员的意见，而不是文献综述或荟萃分析。对于涉及资源有限领域的问题，建议考虑成本效益和更容易获得的可能治疗方法。每个问题都有五到七个相关答案，包括两个非答案。结果实时制表。
结论
本文提出的投票结果和建议可由医生用于支持资源有限地区的极低危、低危和中危 PCa 的管理。个体临床决策应得到现有数据的支持；然而，由于尚未为发展中国家的极低危、低危和中危 PCa 制定治疗指南，因此当面临这种疾病时，本文档将作为参考点。
Zotero 插件