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精神障碍与 COVID-19 的相关性:叙事性综述。

The Correlation between Psychiatric Disorders and COVID-19: A Narrative Review.

机构信息

Health Management Center, the Sixth Medical Center, Chinese PLA General Hospital, NO.6 Fu Cheng Road, Hai Dian District, Beijing, 100048, China,

出版信息

Psychiatr Danub. 2021 Spring;33(1):76-85. doi: 10.24869/psyd.2021.76.

Abstract

Since December 2019, the havoc caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has increased exponentially in a short period of time. As the COVID-19 pandemic is raging around the world, scientists are trying to reveal its mysteriousness. Although COVID-19 is predominantly a respiratory disease, the most common symptoms are fever, dry cough, and fatigue, but extrapulmonary manifestations are increasingly recognized. Recent studies have shown that there is a strong genetic correlation between one or more psychiatric disorders and the occurrence of SARS-CoV-2 infection. Historical epidemiological perspectives and recent neurobiological evidence link infection and psychosis. What is the relationship between COVID-19 and psychiatric disorders? In this article, we will review the correlation between COVID-19 and psychoses, the possible reasons, and the possible pathophysiological mechanisms. The purpose of this review is to provide a reference for clinicians to make correct judgment and treatment when facing patients with COVID-19 and/or psychiatric disorders.

摘要

自 2019 年 12 月以来,严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)在短时间内呈指数级增长。随着 COVID-19 大流行在全球肆虐,科学家们正试图揭开它的神秘面纱。虽然 COVID-19 主要是一种呼吸道疾病,但最常见的症状是发热、干咳和乏力,但越来越多的人认识到肺部外表现。最近的研究表明,一种或多种精神疾病与 SARS-CoV-2 感染的发生之间存在很强的遗传相关性。历史流行病学观点和最近的神经生物学证据将感染与精神病联系起来。COVID-19 和精神疾病之间有什么关系?在本文中,我们将回顾 COVID-19 与精神病之间的相关性、可能的原因以及可能的病理生理学机制。本次综述的目的是为临床医生在面对 COVID-19 和/或精神疾病患者时提供正确判断和治疗的参考。

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