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儿童外侧髁骨不连的手术疗效:一项系统评价与Meta分析

Surgical outcomes in paediatric lateral condyle non-union: A systematic review and meta-analysis.

作者信息

Zhang Siyuan, Tan Si Heng Sharon, Lim Andrew Kean Seng, Hui James Hoi Po

机构信息

Yong Loo Lin School of Medicine, National University of Singapore, 10, Medical Drive 117597, Singapore.

Department of Orthopaedic Surgery, National University Hospital, 1E, Kent Ridge Road, 119228, Singapore.

出版信息

Orthop Traumatol Surg Res. 2022 Feb;108(1):102933. doi: 10.1016/j.otsr.2021.102933. Epub 2021 Apr 15.

Abstract

AIMS

Non-union is a known and much-dreaded complication of paediatric lateral condyle fractures. This systematic review aims to pool together individual studies to find out if the timing of fixation and method of fixation impacts surgical outcomes (postoperative union and elbow ROM) in paediatric lateral condyle non-union.

METHODS

A systematic review and individual patient data meta-analysis was conducted according to PRISMA guidelines. All surgical studies with original data on pediatric lateral humeral condyle non-union were included. Patients who did not undergo surgical fixation were excluded.

RESULTS

A total of 12 studies with 177 patients were included. In total, 159 patients (89.8%) achieved bony union postoperatively while 18 patients (10.2%) did not. Mixed-effects logistic regression showed that percutaneous fixation (p-value=0.020) was associated with lower rates of postoperative union compared to open fixation, whereas the age at surgery did not have a significant impact (p-value=0.401). For elbow ROM, mixed-effects linear regression showed that increased age at surgery (p-value=0.007) and reduction of the fracture fragment (vs. in situ fixation) (p-value=0.041) were associated with reduced postoperative ROM whereas female sex (p-value=0.009) and corrective osteotomy (p-value=0.045) were associated with increased postoperative ROM.

CONCLUSION

While the timing of surgical fixation did not significantly impact postoperative bony union, undergoing fixation at an older age was associated with reduced postoperative elbow ROM. In addition, percutaneous fixation may be associated with poorer postoperative union compared to open fixation while anatomical reduction may be associated with reduced postoperative elbow ROM compared to in situ fixation.

LEVEL OF EVIDENCE

IV.

摘要

目的

骨不连是小儿外侧髁骨折一种常见且令人十分担忧的并发症。本系统评价旨在汇总各项研究,以确定固定时机和固定方法是否会影响小儿外侧髁骨不连的手术效果(术后骨愈合和肘关节活动度)。

方法

根据PRISMA指南进行系统评价和个体患者数据荟萃分析。纳入所有有小儿肱骨外侧髁骨不连原始数据的手术研究。未接受手术固定的患者被排除。

结果

共纳入12项研究,177例患者。总共159例患者(89.8%)术后实现了骨愈合,18例患者(10.2%)未愈合。混合效应逻辑回归显示,与切开复位内固定相比,经皮固定(p值=0.020)术后骨愈合率较低,而手术年龄对其无显著影响(p值=0.401)。对于肘关节活动度,混合效应线性回归显示,手术年龄增加(p值=0.007)和骨折块复位(与原位固定相比)(p值=0.041)与术后活动度降低相关,而女性(p值=0.009)和截骨矫形(p值=0.045)与术后活动度增加相关。

结论

虽然手术固定时机对术后骨愈合无显著影响,但年龄较大时进行固定与术后肘关节活动度降低有关。此外,与切开复位内固定相比,经皮固定术后骨愈合可能较差,而与原位固定相比,解剖复位可能与术后肘关节活动度降低有关。

证据级别

IV级。

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