Pullan Jack, Ayeko Olusegun, Metcalfe James
Department of Trauma and Orthopaedic Surgery, Royal Cornwall Hospitals NHS Trust, Treliske, Truro, Cornwall, TR1 3LJ, United Kingdom.
Department of Trauma and Orthopaedic Surgery, University Hospitals Plymouth NHS Trust, Derriford Hospital, Derriford Road, Plymouth, Devon, PL6 8DH, United Kingdom.
Injury. 2025 Feb;56(2):112155. doi: 10.1016/j.injury.2025.112155. Epub 2025 Jan 11.
Paediatric upper limb fractures are commonly treated with Kirschner (K) wire fixation, which can be buried or left exposed. Although both techniques are widely used, controversy remains regarding infection risk, complications, and other clinical outcomes between buried and exposed K-wires. This systematic review and meta-analysis aimed to compare infection rates and secondary outcomes between buried and exposed K-wires in paediatric upper limb fractures located distal to and including the elbow, and proximal to the carpus.
A systematic review of the literature was conducted according to PRISMA guidelines, with searches performed across Medline, EMBASE, and the Cochrane Library up to July 2023. Studies were included if they directly compared buried and exposed K-wires in paediatric patients (under 18 years old) and reported on infection rates. Meta-analysis was conducted to compare overall infection rates. Pooled means were used to compare secondary outcomes. Bias was assessed using the ROBINS-I and RoB2 tools.
Fifteen studies involving 1,854 participants were included. The meta-analysis showed that buried K-wires were associated with a significantly lower risk of overall postoperative infection compared to exposed K-wires (RR 0.33; 95 % CI 0.22 to 0.50; p< 0.001). The risk of deep infection requiring further surgery was 1.74 % in buried K-wires (95 % CI: 0.72 % to 2.75 %) and 2.07 % in exposed K-wires (95 % CI: 0.55 % to 3.59 %). Skin erosion was a common complication of buried K-wires, with a pooled mean rate of 13.0 %. Buried K-wires were associated with a higher likelihood of requiring removal in theatre (84.4 % vs. 4.2 %). Time to K-wire removal was longer in the buried group (10.9 weeks vs. 5.3 weeks). Re-operation and bone union failure rates were similar between groups.
Our systematic review and meta-analysis suggest that, while buried K-wires are associated with lower overall infection rates, the risk of deep infection is comparable between buried and exposed K-wires. Buried K-wires show higher rates of skin erosion and increased need for removal in theatre. Given these findings, exposed K-wires offer a safe and more cost-effective option for paediatric upper limb fracture fixation. Further studies are needed to assess patient-reported outcomes and environmental impacts.
小儿上肢骨折通常采用克氏针固定治疗,克氏针可埋入或外露。尽管这两种技术都被广泛应用,但关于埋入式和外露式克氏针在感染风险、并发症及其他临床结局方面仍存在争议。本系统评价和荟萃分析旨在比较埋入式和外露式克氏针在肘部及以下、腕部及以上小儿上肢骨折中的感染率和次要结局。
根据PRISMA指南对文献进行系统评价,检索截至2023年7月的Medline、EMBASE和Cochrane图书馆。纳入直接比较小儿患者(18岁以下)埋入式和外露式克氏针并报告感染率的研究。进行荟萃分析以比较总体感染率。采用合并均值比较次要结局。使用ROBINS-I和RoB2工具评估偏倚。
纳入15项研究,共1854名参与者。荟萃分析表明,与外露式克氏针相比,埋入式克氏针术后总体感染风险显著更低(风险比0.33;95%置信区间0.22至0.50;p<0.001)。埋入式克氏针需要进一步手术的深部感染风险为1.74%(95%置信区间:0.72%至2.75%),外露式克氏针为2.07%(95%置信区间:0.55%至3.59%)。皮肤侵蚀是埋入式克氏针的常见并发症,合并平均发生率为13.0%。埋入式克氏针在手术室需要取出的可能性更高(84.4%对4.2%)。埋入组克氏针取出时间更长(10.9周对5.3周)。两组再次手术和骨愈合失败率相似。
我们的系统评价和荟萃分析表明,虽然埋入式克氏针总体感染率较低,但埋入式和外露式克氏针的深部感染风险相当。埋入式克氏针皮肤侵蚀率更高,在手术室取出的需求增加。鉴于这些发现,外露式克氏针为小儿上肢骨折固定提供了一种安全且更具成本效益的选择。需要进一步研究以评估患者报告的结局和环境影响。