Department of Thoracic Surgery, "Timofei Moșneaga" Republican Clinical Hospital, Chișinău, Republic of Moldova.
Am J Otolaryngol. 2021 Sep-Oct;42(5):103020. doi: 10.1016/j.amjoto.2021.103020. Epub 2021 Apr 5.
Flexible endoscopic laser surgery (FELS) is able to overcome some limitations of traditional transoral CO2 laser surgery. The objective of this study was to assess the efficacy of FELS in the treatment of T1-T2 glottic carcinoma.
We applied FELS for 120 patients with T1-T2 glottic carcinoma. Tumour ablation was performed with Nd:YAG laser. In 76 (63.3%) cases the intervention was performed under local anesthesia. Twenty nine (24.2%) patients (T1b - 2, T2-27) underwent postoperative radiation therapy (RT).
Successful treatment, with local control and larynx preservation, was obtained in 106 cases (88.3%), with mean follow-up of 6.4 years. More than 50% of the patients were followed-up over 5 years.
FELS can be proposed as an alternative treatment method for patients with early glottic carcinoma. The advantages of the method include: possibility of applying treatment under local anesthesia, that allows avoiding of general anesthesia and its related risks; applicability to patients with contraindications to general anesthesia and patients with anatomic particularities, that make transoral microsurgery impossible, allowing avoidance of the laryngofissure and tracheotomy.
灵活内镜激光手术（FELS）能够克服传统经口 CO2 激光手术的一些局限性。本研究的目的是评估 FELS 在治疗 T1-T2 声门型喉癌中的疗效。
我们应用 FELS 治疗了 120 例 T1-T2 声门型喉癌患者。肿瘤消融采用 Nd:YAG 激光进行。在 76 例（63.3%）患者中，在局部麻醉下进行干预。29 例（24.2%）患者（T1b-2，T2-27）接受了术后放射治疗（RT）。
106 例（88.3%）患者获得了局部控制和保留喉的成功治疗，平均随访时间为 6.4 年。超过 50%的患者随访时间超过 5 年。
FELS 可作为早期声门型喉癌患者的一种替代治疗方法。该方法的优点包括：在局部麻醉下进行治疗的可能性，这可以避免全身麻醉及其相关风险；适用于全身麻醉禁忌的患者和解剖特殊的患者，使经口微创手术无法进行，避免了喉裂开和气管切开。
