Lille F, Hazemann P, Garnier R, Dally S
UA CNRS 385, CHU Pitié Salpétrière, Paris, France.
J Toxicol Clin Toxicol. 1988;26(1-2):103-16. doi: 10.3109/15563658808995401.
Pattern reversal, brain stem auditory and somatosensory evoked potentials (PREPs, BAEPs, SEPs) have been recorded on 13 patients occupationally exposed to inorganic lead compounds, in 9 patients occupationally or accidentally exposed to inorganic mercury compounds and in 26 chronic alcoholics. The results were compared to those of a normal control group. Peripheral conduction velocities were decreased in lead exposed workers and in alcoholics, but not modified in the mercury exposed patients. In the three exposed groups, an amplitude increase (PREPs and upper limb SEP cortical components), more important in the mercury group and an increase of central conduction time in case of lower limb stimulation, could be interpreted as early signs of nervous cortical impairment.
对13名职业性接触无机铅化合物的患者、9名职业性或意外接触无机汞化合物的患者以及26名慢性酒精中毒者记录了图形翻转、脑干听觉和体感诱发电位（PREPs、BAEPs、SEPs）。将结果与正常对照组的结果进行了比较。铅暴露工人和酗酒者的外周传导速度降低，但汞暴露患者的外周传导速度未改变。在这三个暴露组中，幅度增加（PREPs和上肢SEP皮层成分）在汞组中更明显，以及下肢刺激时中枢传导时间增加，可被解释为神经皮层损伤的早期迹象。
