Department of Obstetrics and Gynecology, St. Vincent's hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Department of Obstetrics and Gynecology, Seoul St. Mary's hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Int J Med Sci. 2021 Mar 21;18(10):2204-2208. doi: 10.7150/ijms.55026. eCollection 2021.
Compare the oncologic outcomes of patients with intermediate-risk endometrial cancer who were staged by minimally invasive surgery with the outcomes of patients who underwent open surgery. Data from 206 patients with intermediate-risk endometrial cancer who were treated between January 2009 and January 2019 were reviewed. The patients' data were retrieved from five institutions. The patients were divided into two groups: those who underwent open surgery and those who underwent minimally invasive surgery. Tumor characteristics, recurrence rate, disease-free survival, and overall survival were compared according to surgical approach. Among the 206 patients included in this study, 76 underwent open surgery (36.9%) and 130 underwent MIS (63.1%). In patients with stage IB endometrial cancer, the recurrence rate, disease-free survival, and overall survival were not significantly different between those who underwent minimally invasive surgery and those who underwent open surgery. However, in patients with stage II endometrial cancer, the recurrence rate was significantly higher among those who underwent minimally invasive surgery (37.5% vs. 5.3%, p = 0.013). Patients with stage II endometrial cancer who underwent minimally invasive surgery had a significantly lower disease-free survival (p = 0.012) than those who underwent open surgery, however, the overall survival (p = 0.252) was similar between the two groups. Minimally invasive surgery results in less favorable survival outcomes than open surgery in patients with stage II endometrial cancer.
比较接受微创手术分期的中危子宫内膜癌患者与接受开腹手术患者的肿瘤学结局。回顾了 2009 年 1 月至 2019 年 1 月期间治疗的 206 例中危子宫内膜癌患者的数据。这些患者的数据来自五家机构。将患者分为两组：接受开腹手术的患者和接受微创手术的患者。根据手术方式比较肿瘤特征、复发率、无病生存率和总生存率。在这项研究中纳入的 206 例患者中，76 例接受开腹手术（36.9%），130 例接受 MIS（63.1%）。在 IB 期子宫内膜癌患者中，接受微创手术和开腹手术的患者复发率、无病生存率和总生存率无显著差异。然而，在 II 期子宫内膜癌患者中，接受微创手术的患者复发率明显更高（37.5% vs. 5.3%，p=0.013）。接受微创手术的 II 期子宫内膜癌患者无病生存率显著低于接受开腹手术的患者（p=0.012），但两组总生存率（p=0.252）相似。在 II 期子宫内膜癌患者中，微创手术的生存结局不如开腹手术。
