Cancer Healthcare Research Branch, Center for Uterine Cancer, and Center for Clinical Trials, National Cancer Center, Goyang, Korea.
Cancer Registration and Statistics Branch, National Cancer Center, Goyang, Korea.
J Gynecol Oncol. 2019 Jan;30(1):e38. doi: 10.3802/jgo.2019.30.e38.
To investigate the incidence and trends of cervical (C53), endometrial (C54.1), and ovarian cancer (C56) among Korean females between 1999 and 2015.
The incidence of the three major gynecological cancers between 1999 and 2015 was analyzed based on the data from the Korea Central Cancer Registry. The age-standardized rates (ASRs) and the annual percent changes (APCs) for each site were calculated.
The absolute incidence rates of the three major gynecological cancers increased from 6,394 in 1999 to 8,288 in 2015. ASR for gynecologic cancer decreased from 23.7 per 100,000 in 1999 to 21.1 in 2015. This was mainly due to a definitive decrease in the incidence of cervical cancer, which recorded an APC of -3.7%. The trends of APC for gynecologic cancer were variable, being -1.36% between 1999 and 2006 and -0.11% between 2006 and 2015. A definitive but variable increase was noted for endometrial cancer, and the APC for this cancer was 7.4% between 1999 and 2009 and 3.5% between 2009 and 2015. The incidence of ovarian cancer gradually increased, with an APC of 1.8% between 1999 and 2015.
Overall, ASRs and APCs for the three major gynecological cancers are decreasing, with a recent reduction in the width of the change. However, there has been a progressive increase in the incidence of endometrial and ovarian cancers.
调查 1999 年至 2015 年期间韩国女性中宫颈（C53）、子宫内膜（C54.1）和卵巢癌（C56）的发病率和趋势。
基于韩国中央癌症登记处的数据，分析了 1999 年至 2015 年期间三种主要妇科癌症的发病率。计算了每个部位的年龄标准化率（ASR）和年百分比变化（APC）。
三种主要妇科癌症的绝对发病率从 1999 年的 6394 例上升至 2015 年的 8288 例。妇科癌症的 ASR 从 1999 年的每 100,000 人 23.7 例下降至 2015 年的 21.1 例。这主要是由于宫颈癌发病率的明确下降，其 APC 为-3.7%。妇科癌症的趋势各不相同，1999 年至 2006 年为-1.36%，2006 年至 2015 年为-0.11%。子宫内膜癌则呈现明确但可变的上升趋势，1999 年至 2009 年的 APC 为 7.4%，2009 年至 2015 年为 3.5%。卵巢癌的发病率逐渐上升，1999 年至 2015 年的 APC 为 1.8%。
总体而言，三种主要妇科癌症的 ASR 和 APC 呈下降趋势，变化幅度近期有所缩小。然而，子宫内膜癌和卵巢癌的发病率呈逐渐上升趋势。
