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一名Ⅰ型成骨不全产妇剖宫产的麻醉管理

The Anesthetic Management of a Parturient With Osteogenesis Imperfecta Type I Undergoing Cesarean Delivery.

作者信息

Yan Manshu, Knowland Nicholas P, Lien Donna

机构信息

Anesthesiology and Perioperative Medicine, Loma Linda University Medical Center, Loma Linda, USA.

出版信息

Cureus. 2021 Mar 12;13(3):e13849. doi: 10.7759/cureus.13849.

Abstract

Osteogenesis imperfecta (OI) is a rare disorder of bone fragility caused by mutations in the COL1A1/2 genes, which encode type I procollagen. It commonly manifests with bone fractures, joint dislocations, and easy bruising. OI patients presenting for surgery may pose multiple challenges to the anesthesiologist such as management of a potentially difficult airway and heightened positional fracture risks. We present a case detailing the spinal anesthetic management of a 28-year-old woman with type I OI requiring cesarean delivery for a 32-week intrauterine pregnancy with fetal cardiac anomalies.

摘要

成骨不全症(OI)是一种由编码I型前胶原的COL1A1/2基因突变引起的罕见骨脆性疾病。它通常表现为骨折、关节脱位和易出现瘀伤。接受手术的OI患者可能给麻醉医生带来多重挑战,例如潜在困难气道的管理以及体位性骨折风险增加。我们报告一例详细病例,该病例为一名28岁I型OI女性,因32周宫内妊娠合并胎儿心脏异常需要剖宫产,介绍了其脊髓麻醉管理情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8870/8038905/015428679a00/cureus-0013-00000013849-i01.jpg

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