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克罗恩病患者并发大肠杆菌性胸壁脓肿伴肋骨骨髓炎1例罕见病例

A Rare Case of Escherichia coli Chest Wall Abscess With Rib Osteomyelitis in a Patient With Crohn's Disease.

作者信息

Dadlani Apaar, Bandikatla Sudeepthi, Koch Jennifer A

机构信息

Internal Medicine, University of Louisville School of Medicine, Louisville, USA.

出版信息

Cureus. 2021 Mar 12;13(3):e13860. doi: 10.7759/cureus.13860.

Abstract

Primary chest wall abscess due to hematogenous spread is very rare and has seldom been documented in the literature, with most reported cases attributed to . Prompt diagnosis and management with antibiotics, and evacuation of the abscess, is imperative as the infection can lead to systemic or disseminated infection, including erosion into surrounding bone if left untreated. We describe the case of a 67-year-old female with severe Crohn's disease receiving anti-tumor necrosis factor-alpha (TNF-α) therapy, Etanercept presenting with localized () chest wall abscess with erosion into the surrounding rib. This case highlights a rare clinical entity, chest wall abscess, which is also an unusual site of infection. Only three previous cases of primary chest wall abscess can be found in the published literature. This case also highlights a possible association of severe Crohn's disease predisposing to complicated soft tissue infection.

摘要

血源性播散所致的原发性胸壁脓肿非常罕见,文献中鲜有记载,大多数报道的病例归因于……。由于感染若不治疗可导致全身或播散性感染,包括侵蚀周围骨质,因此及时使用抗生素诊断和治疗并引流脓肿至关重要。我们描述了一例67岁患有严重克罗恩病且正在接受抗肿瘤坏死因子-α(TNF-α)治疗(依那西普)的女性病例,该患者出现局限性()胸壁脓肿并侵蚀周围肋骨。本病例突出了一种罕见的临床实体——胸壁脓肿,它也是一个不常见的感染部位。在已发表的文献中仅能找到三例原发性胸壁脓肿的先前病例。本病例还突出了严重克罗恩病可能易引发复杂软组织感染的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e305/8038915/b1d0ceb6ec69/cureus-0013-00000013860-i01.jpg

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