Podrazký V, Stokrová S, Fric I
Connect Tissue Res. 1975;4(1):51-4. doi: 10.3109/03008207509152197.
The interaction between alpha-elastin and a connective tissue proteoglycan was followed by optical density measurements and circular dichroism spectroscopy. It was found that interaction takes place at pH values below the isoelectric point of elastin with the formation of a complex coacervate. CD spectra demonstrated conformational changes of alpha-elastin caused by the interaction and resulting in an increase in the content of helical structure. This finding suggests the possibility of the involvement of proteoglycans in the molecular organization of elastin.
通过光密度测量和圆二色光谱法研究了α-弹性蛋白与结缔组织蛋白聚糖之间的相互作用。结果发现，相互作用发生在低于弹性蛋白等电点的pH值下，并形成了复合凝聚层。圆二色光谱显示α-弹性蛋白因相互作用而发生构象变化，导致螺旋结构含量增加。这一发现表明蛋白聚糖可能参与了弹性蛋白的分子组织。
