Ciani Francesca, Maruccio Lucianna, Cocchia Natascia, d'Angelo Danila, Carotenuto Domenico, Avallone Luigi, Namagerdi Asadoor Amirkhani, Tafuri Simona
Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
These authors contributed equally.
J Adv Vet Anim Res. 2021 Mar 11;8(1):173-184. doi: 10.5455/javar.2021.h500. eCollection 2021 Mar.
Assisted reproductive technologies (ARTs) are widely used as a tool to improve reproductive performance in both humans and animals. In particular, in the veterinary field, ARTs are used to improve animal genetics, recover endangered animals, and produce offspring in the event of subfertility or infertility in males or females. However, the use of ARTs did not improve the fertilization rate in some animals due to various factors such as the difficulty in reproducing an anatomical and humoral substrate typical of the natural condition or due to the increase in catabolites and their difficult elimination. The environment allows the production and increase in the concentration of substances, including reactive oxygen species (ROS), which could be harmful to gametes. If produced in high concentration, the ROS becomes deleterious, both and systems. It has been seen that the use of antioxidants can help neutralize or counteract the production of ROS. The present study aims to report the latest findings regarding the use of antioxidants in ARTs of some domestic species, such as dogs, cats, and horses, compared to other animal species, such as cattle, in which ARTs have instead developed more widely.
辅助生殖技术（ARTs）被广泛用作提高人类和动物繁殖性能的工具。特别是在兽医领域，ARTs被用于改善动物遗传、拯救濒危动物，以及在雄性或雌性出现亚生育力或不育的情况下繁殖后代。然而，由于各种因素，如难以重现自然条件下典型的解剖和体液环境，或由于分解代谢产物增加及其难以消除，ARTs在某些动物中的受精率并未得到提高。环境会导致包括活性氧（ROS）在内的物质产生并使其浓度增加，而这些物质可能对配子有害。如果ROS以高浓度产生，它会对生殖系统的细胞和分子系统都产生有害影响。已经发现，使用抗氧化剂有助于中和或抵消ROS的产生。本研究旨在报告与其他动物物种（如牛，其ARTs发展更为广泛）相比，在一些家养物种（如狗、猫和马）的ARTs中使用抗氧化剂的最新研究结果。
