Department of Thoracic Surgery, Kartal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Department of Obstetrics and Gynecology, Kartal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Rev Bras Ginecol Obstet. 2021 Mar;43(3):200-206. doi: 10.1055/s-0041-1726054. Epub 2021 Apr 15.
Covid-19 became a pandemic, and researchers have not been able to establish a treatment algorithm. The pregnant population is also another concern for health care professionals. There are physiological changes related to pregnancy that result in different laboratory levels, radiological findings and disease progression. The goal of the present article is to determine whether the laboratory results and radiological findings were different in non-pregnant women (NPWs) of reproductive age and pregnant women (PWs) diagnosed with the Covid-19 infection.
Out of 34 patients, 15 (44.11%) PWs and 19 (55.8%) NPWs were included in the study. Age, comorbidities, complaints, vitals, respiratory rates, computed tomography (CT) findings and stages, as well as laboratory parameters, were recorded from the hospital database.
The mean age of the PWs was of 27.6 ± 0.99 years, and that of the NPWs was of 37.63 ± 2.00; when age was compared between the groups, a statistically significant difference ( = 0.001) was found. The mean systolic blood pressure of the PWs was of 116.53 ± 11.35, and that of the NPWs was of 125.53 ± 13.00, and their difference was statistically significant ( = 0.05). The difference in the minimum respiratory rates of the patients was also statistically significant ( = 0.05). The platelet levels observed among the PWs with Covid-19 were lower than those of the NPWs (185.40 ± 39.09 × 109/mcL and 232.00 ± 71.04 × 109/mcL respectively; = 0.05). The mean D-dimer value of the PWs was lower in comparison to that of the NPWs ( < 0.05).
The laboratory findings and imaging studies may differ between pregnant and non-pregnant populations. It is important to properly interpret these studies. Future studies with a higher number of patients are required to confirm these preliminary data.
Covid-19 已成为大流行疾病,但研究人员尚未能够建立治疗方案。孕妇也是医疗保健专业人员关注的另一个问题。怀孕会引起与生理相关的变化,从而导致不同的实验室水平、影像学发现和疾病进展。本文的目的是确定在诊断为 Covid-19 感染的非妊娠育龄妇女(NPWs)和孕妇(PWs)中,实验室结果和影像学发现是否存在差异。
在 34 名患者中,纳入了 15 名(44.11%)PWs 和 19 名(55.8%)NPWs。从医院数据库中记录了年龄、合并症、症状、生命体征、呼吸频率、计算机断层扫描(CT)结果和分期以及实验室参数。
PWs 的平均年龄为 27.6±0.99 岁,NPWs 的平均年龄为 37.63±2.00 岁;当比较两组的年龄时,差异具有统计学意义( = 0.001)。PWs 的平均收缩压为 116.53±11.35mmHg,NPWs 的平均收缩压为 125.53±13.00mmHg,差异具有统计学意义( = 0.05)。患者的最低呼吸频率差异也具有统计学意义( = 0.05)。患有 Covid-19 的 PWs 的血小板水平低于 NPWs(分别为 185.40±39.09×109/mcL 和 232.00±71.04×109/mcL; = 0.05)。与 NPWs 相比,PWs 的平均 D-二聚体值较低( < 0.05)。
孕妇和非孕妇人群的实验室检查结果和影像学研究可能存在差异。正确解读这些研究结果非常重要。需要进行更多患者的未来研究来证实这些初步数据。