Department of Nursing, National Center for Geriatrics and Gerontology, Obu-shi, Aichi-ken, Japan.
Department of Nursing, School of Human Health Sciences, Nagoya University Graduate School of Medicine, Nagoya-shi, Aichi-ken, Japan.
Eur Geriatr Med. 2021 Oct;12(5):1003-1009. doi: 10.1007/s41999-021-00491-7. Epub 2021 Apr 16.
To examine the relationship of diabetes-related foot disease (DFD) with diabetes and age-related complications in older patients with diabetes mellitus (DM).
We examined 562 outpatients with diabetes, aged ≥ 65 years, for DFD. The variables collected in this study were demographics, DM-related complications, treatment method, and age-related complications. Differences in the complications were compared between patients with and without DFD. Logistic regression analysis was used to determine the associations of DFD with DM and age-related complications.
A total of 246 patients (43.8%) had DFD. Logistic regression analysis identified low grip strength [Odds ratio (OR): 1.83, 95% confidence interval (CI) 1.21-2.76), hypertension (OR: 1.81, 95% CI 1.09-3.00), and diabetes-related peripheral neuropathy (DPN) (OR: 1.92, 95% CI 1.24-2.98) to be significantly associated with DFD. Patients with DPN and hypertension had a higher risk of DFD than patients with DPN or hypertension alone. Individuals with DPN and low grip strength (OR: 1.74, 95% CI 1.09-2.81) were at a lower risk than those with low grip strength alone.
Hypertension, DPN, and low grip strength were significantly associated with DFD in older patients with DM, with the risk of DFD being higher in patients with both DPN and hypertension. When considering DFD in older patients with DM, low grip strength should be considered equally important as a DM-related complication.
探讨糖尿病相关足部疾病（DFD）与老年糖尿病患者的糖尿病和年龄相关并发症的关系。
我们检查了 562 名年龄≥65 岁的糖尿病门诊患者的 DFD。本研究收集的变量包括人口统计学、糖尿病相关并发症、治疗方法和年龄相关并发症。比较了有和无 DFD 的患者的并发症差异。使用逻辑回归分析确定 DFD 与糖尿病和年龄相关并发症的关系。
共有 246 名患者（43.8%）患有 DFD。逻辑回归分析确定低握力（优势比 [OR]：1.83，95%置信区间 [CI]：1.21-2.76）、高血压（OR：1.81，95% CI：1.09-3.00）和糖尿病相关周围神经病变（DPN）（OR：1.92，95% CI：1.24-2.98）与 DFD 显著相关。患有 DPN 和高血压的患者比仅患有 DPN 或高血压的患者发生 DFD 的风险更高。患有 DPN 和低握力的个体（OR：1.74，95% CI：1.09-2.81）比仅低握力的个体发生 DFD 的风险更低。
高血压、DPN 和低握力与老年糖尿病患者的 DFD 显著相关，患有 DPN 和高血压的患者 DFD 的风险更高。在考虑老年糖尿病患者的 DFD 时，应与糖尿病相关并发症同等重视低握力。
