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[重症早产儿和新生儿QT间期的短暂延长]

[Transitory prolongation of QT time in severely ill premature and newborn infants].

作者信息

Möller J C, Tegtmeyer F K, Rose T

机构信息

Klinik für Kinderheilkunde der Medizinischen Universität zu Lübeck.

出版信息

Klin Padiatr. 1988 Mar-Apr;200(2):128-32. doi: 10.1055/s-2008-1033698.

Abstract

Over 24 months in a Neonatal Intensive Care Unit 118 electrocardiograms were recorded in the first three days of life. 12 preterm and term newborns had a corrected QT-time-prolongation over 0.44 s. Measurement of the ionized calcium level in these children revealed hypocalcemia in only four as a reason for QT-time-prolongation. One child had hypokalemia, one child suffered from accidental Bupivacain injection. In the other six children no known reasons for QT-time-prolongation could be found. The QT-time-prolongation persisted for a maximum of three months, no inherited QT-syndrome existed. We discuss a correlation of these transitory QT-time-prolongation with asphyxia which preexisted in all six children. Influences on catecholamine receptors of myocardium or changes in central sympathicotonus may be assumed.

摘要

在新生儿重症监护病房的24个月期间,在出生后的头三天记录了118份心电图。12名早产儿和足月儿的校正QT间期延长超过0.44秒。对这些儿童的离子钙水平进行测量后发现,只有4名儿童存在低钙血症,这是QT间期延长的原因。1名儿童有低钾血症,1名儿童意外注射了布比卡因。在其他6名儿童中,未发现QT间期延长的已知原因。QT间期延长最长持续了三个月,不存在遗传性QT综合征。我们讨论了这些暂时性QT间期延长与所有6名儿童先前存在的窒息之间的相关性。可以推测这对心肌的儿茶酚胺受体有影响或中枢交感神经张力发生了变化。

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