Hygiene and Public Health Unit, Department of Cardiac Thoracic and Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Hygiene and Public Health Unit, Department of Cardiac Thoracic and Vascular Sciences and Public Health, University of Padua, Padua, Italy
BMJ Glob Health. 2021 Apr;6(4). doi: 10.1136/bmjgh-2020-004140.
The 2030 Agenda for Sustainable Development aims to reduce neonatal mortality to at least 12 per 1000 live births. Most of the causes can be prevented or cured. Access to quality healthcare during pregnancy and labour is the key to reduce perinatal deaths, and maternity waiting homes (MWHs) may have an impact, especially for women who live far from the healthcare system. We conducted a case-control study to evaluate the effectiveness of MWH in reducing perinatal mortality in a secondary hospital in Ethiopia.
We did a nested case-control study from January 2014 through December 2017. The enrolled cases were mothers whose childbirth resulted in stillbirth or early neonatal death. The controls were mothers with an alive baby at 7 days or with an alive baby on discharge. We collected demographic, anamnestic, pregnancy-related and obstetric-related data. The effectiveness of the MWH on perinatal death was assessed by a logistic regression model, adjusted for all other variables investigated as potential confounders. We also did a sensitivity analysis to explore the role of twin pregnancies.
We included 1175 cases and 2350 controls. The crude analysis showed a protective effect of the MWH towards perinatal mortality (OR=0.700; 95% CI: 0.505 to 0.972), even more protective after adjustment for confounders (adjusted OR (AOR)=0.452; 95% CI: 0.293 to 0.698). Sensitivity analyses showed a consistent result, even excluding twin pregnancies (AOR=0.550; 95% CI: 0.330 to 0.917).
MWHs appear to reduce perinatal mortality by 55%. Our findings support the decision to invest in MWH to support pregnant women with higher quality and more comprehensive healthcare strategy, including quality antenatal care in peripheral primary care clinics, where risk factors can be recognised and women can be addressed for admission to MWH.
可持续发展目标 2030 旨在将新生儿死亡率降低到每 1000 例活产儿 12 例以下。大多数病因都可以预防或治愈。在妊娠和分娩期间获得优质医疗保健是降低围产期死亡的关键,而母婴等候之家(MWH)可能会产生影响,特别是对于远离医疗保健系统的妇女。我们在埃塞俄比亚的一家二级医院进行了一项病例对照研究,以评估 MWH 在降低围产期死亡率方面的效果。
我们在 2014 年 1 月至 2017 年 12 月进行了一项嵌套病例对照研究。纳入的病例是分娩导致死产或新生儿早期死亡的母亲。对照组是 7 天活产或出院时活产的母亲。我们收集了人口统计学、病史、妊娠相关和产科相关数据。通过逻辑回归模型评估 MWH 对围产儿死亡的有效性,该模型调整了所有其他被视为潜在混杂因素的变量。我们还进行了敏感性分析,以探讨双胞胎妊娠的作用。
我们纳入了 1175 例病例和 2350 例对照。初步分析显示,MWH 对围产儿死亡率具有保护作用(OR=0.700;95%CI:0.505 至 0.972),在调整混杂因素后更为保护(调整后的 OR(AOR)=0.452;95%CI:0.293 至 0.698)。敏感性分析显示,即使排除双胞胎妊娠,结果也一致(AOR=0.550;95%CI:0.330 至 0.917)。
MWH 似乎使围产儿死亡率降低了 55%。我们的研究结果支持投资 MWH 的决策,以支持孕妇提供更高质量和更全面的医疗保健策略,包括在基层初级保健诊所提供优质的产前护理,以便识别风险因素并为孕妇提供入住 MWH 的机会。