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脉络膜痣与葡萄膜黑色素瘤并存伴巩膜色素播散表现为眼球痨。

Concurrence of peripunctal nevus and uveal melanoma with scleral pigment dispersion presenting as phthisis bulbi.

机构信息

Ocular Oncology, The Operation Eyesight Univeraal Institute for Eye Cancer, LV Prasad Eye Institute, Hyderabad, Telangana, India.

Ophthalmic Pathology Services, LV Prasad Eye Institute, Hyderabad, Telangana, India.

出版信息

BMJ Case Rep. 2021 Apr 16;14(4):e240854. doi: 10.1136/bcr-2020-240854.

DOI:10.1136/bcr-2020-240854
PMID:33863771
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8055113/
Abstract

This case report demostrates an unusual occurence of peripunctal nevus and uveal melanoma, in which the clinical diganosis of uveal melanoma was masked by the atypical presentation as phthisis bulbi. Nevertheless, peculiar scleral pigment hinted at a possible intraocular tumour. The importance of meticulous clinical examination in assessment of ocular and periocular pigmented lesions is demonstrated. Further, clinicopathological differentials of correlation scleral pigmentation in diffuse necrotic uveal melanoma are illustrated.

摘要

本病例报告展示了一种不同寻常的现象，即围睛部痣和葡萄膜黑色素瘤，其中葡萄膜黑色素瘤的临床诊断被典型的眼球痨表现所掩盖。然而，巩膜的特殊色素提示可能存在眼内肿瘤。本病例强调了细致的临床检查在评估眼部和眼周色素性病变中的重要性。此外，还阐述了弥漫性坏死性葡萄膜黑色素瘤中巩膜色素沉着的临床病理鉴别。

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Concurrence of peripunctal nevus and uveal melanoma with scleral pigment dispersion presenting as phthisis bulbi.脉络膜痣与葡萄膜黑色素瘤并存伴巩膜色素播散表现为眼球痨。
BMJ Case Rep. 2021 Apr 16;14(4):e240854. doi: 10.1136/bcr-2020-240854.
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本文引用的文献

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Posterior uveal melanoma in 321 Asian Indian patients: analysis based on the 8th edition of American Joint Committee Cancer classification.321 例亚裔印度人葡萄膜黑色素瘤患者：基于第 8 版美国联合癌症分类的分析。
Int Ophthalmol. 2020 Nov;40(11):3087-3096. doi: 10.1007/s10792-020-01494-2. Epub 2020 Jun 29.
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Spontaneous Necrosis of a Large Choroidal Melanoma: Unusual Presentation in a 49-Year-Old Male.一例大脉络膜黑色素瘤的自发性坏死：一名49岁男性的罕见表现。
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Choroidal melanoma presenting with anterior segment involvement and phthisis bulbi.伴有眼前节受累及眼球痨的脉络膜黑色素瘤。
BMJ Case Rep. 2013 Dec 10;2013:bcr2013200793. doi: 10.1136/bcr-2013-200793.
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The clinicopathological spectrum of benign peripunctal tumours.良性睑周肿瘤的临床病理谱
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Unsuspected intraocular malignant melanomas.隐匿性眼内恶性黑色素瘤
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Malignant melanoma and massive retinal gliosis in phthisis bulbi.眼球痨中的恶性黑色素瘤和大量视网膜胶质增生。
Eye (Lond). 2002 Nov;16(6):781-2. doi: 10.1038/sj.eye.6700217.
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Enucleation versus evisceration.眼球摘除术与眼内容剜出术
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9
Peripapillary venous drainage from the choroid: a variable feature in human eyes.脉络膜的视乳头周围静脉引流：人类眼睛中的一个可变特征。
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Pigmented conjunctival and scleral lesions.色素沉着性结膜和巩膜病变。
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