间苯三酚用于加速分娩的疗效：系统评价和荟萃分析。
Efficacy of phloroglucinol for acceleration of labour: a systematic review and meta‑analysis.
机构信息
Department of Pharmacy, School of Medicine, Women's Hospital, Zhejiang University, Hangzhou, 310006, China.
出版信息
Arch Gynecol Obstet. 2021 Aug;304(2):421-428. doi: 10.1007/s00404-021-06043-5. Epub 2021 Apr 17.
PURPOSE
To assess the efficacy of phloroglucinol for acceleration of labour.
METHODS
Randomized controlled trials (RCTs) comparing phloroglucinol with placebo were searched in PubMed, Embase and the Cochrane Library. Literatures were collected up to April 2020. Primary outcomes were the duration of labour and average blood loss. Finally, a total of 4 RCTs, 377 patients were included in this meta-analysis. The included RCTs were analyzed by the software Rev Man 5. 3.
RESULTS
In the phloroglucinol group, the duration of the first stage was reduced by 116.04 min (95% CI 107.71 to 124.68), and the duration of the second stage was reduced by 10.75 min (95% CI 8.79 to 12.70). The average blood loss was reduced by 16.07 ml, which was statistically different from the control group.
CONCLUSION
The application of phloroglucinol is proved to be effective for accelerating the labour process, reducing the risk of maternal and neonatal complications.
目的
评估间苯三酚加速分娩的疗效。
方法
在 PubMed、Embase 和 Cochrane Library 中检索了间苯三酚与安慰剂进行比较的随机对照试验（RCT）。文献收集截至 2020 年 4 月。主要结局指标为产程时间和平均失血量。最终，这项荟萃分析共纳入了 4 项 RCT，377 名患者。使用 RevMan 5.3 软件对纳入的 RCT 进行分析。
结果
间苯三酚组第一产程时间减少 116.04 分钟（95%CI 107.71 至 124.68），第二产程时间减少 10.75 分钟（95%CI 8.79 至 12.70）。平均失血量减少 16.07ml，与对照组相比有统计学差异。
结论
间苯三酚的应用被证明能有效加速分娩过程，降低母婴并发症的风险。
Zotero 插件