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Mucus Plugs: A Treatable Trait for Preventing COPD Exacerbations.黏液栓：预防慢性阻塞性肺疾病急性加重的可治疗特征。
Am J Respir Crit Care Med. 2024 Nov 12;211(5):685-6. doi: 10.1164/rccm.202410-2081ED.
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Is There a Correlation Between the Location of the Clot in the Pulmonary Arterial Tree with the Location of the Mucus Plug in the Pulmonary Bronchial Tree in Patients with chronic obstructive pulmonary disease Experiencing Pulmonary Embolism? Novel Findings.慢性阻塞性肺疾病合并肺栓塞患者肺动脉树内血栓位置与肺支气管树内黏液栓位置之间是否存在相关性？新发现。
Thorac Res Pract. 2024 Nov 1;25(6):203-208. doi: 10.5152/ThoracResPract.2024.23137.
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Airway Mucus Plugs on Chest Computed Tomography Are Associated with Exacerbations in COPD.胸部计算机断层扫描显示的气道黏液栓与慢性阻塞性肺疾病急性加重相关。
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Symptomatic smokers without COPD have physiological changes heralding the development of COPD.没有慢性阻塞性肺疾病（COPD）的有症状吸烟者存在预示着COPD发展的生理变化。
ERJ Open Res. 2022 Jun 27;8(2). doi: 10.1183/23120541.00202-2022. eCollection 2022 Apr.
9
Mucus Plugs and Small Airway Dysfunction: An Important Concept in Airway Disease Pathophysiology.
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本文引用的文献

1
Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers.黏液栓与肺气肿在吸烟人群气流阻塞与低氧血症发病机制中的作用
Am J Respir Crit Care Med. 2021 Apr 15;203(8):957-968. doi: 10.1164/rccm.202006-2248OC.
2
Luminal Plugging on Chest CT Scan: Association With Lung Function, Quality of Life, and COPD Clinical Phenotypes.胸部 CT 扫描中的管腔堵塞：与肺功能、生活质量和 COPD 临床表型的关联。
Chest. 2020 Jul;158(1):121-130. doi: 10.1016/j.chest.2019.12.046. Epub 2020 Feb 1.
3
CT and Functional MRI to Evaluate Airway Mucus in Severe Asthma.CT 和功能性磁共振成像评估严重哮喘的气道黏液。
Chest. 2019 Jun;155(6):1178-1189. doi: 10.1016/j.chest.2019.02.403. Epub 2019 Mar 23.
4
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction.哮喘患者的黏液栓与嗜酸性粒细胞增多和气流阻塞有关。
J Clin Invest. 2018 Mar 1;128(3):997-1009. doi: 10.1172/JCI95693. Epub 2018 Feb 5.
5
Chronic bronchitis and current smoking are associated with more goblet cells in moderate to severe COPD and smokers without airflow obstruction.慢性支气管炎和当前吸烟与中重度慢性阻塞性肺疾病（COPD）患者以及无气流受限的吸烟者中更多的杯状细胞有关。
PLoS One. 2015 Feb 3;10(2):e0116108. doi: 10.1371/journal.pone.0116108. eCollection 2015.
6
The chronic bronchitis phenotype in chronic obstructive pulmonary disease: features and implications.慢性阻塞性肺疾病中的慢性支气管炎表型：特征与影响
Curr Opin Pulm Med. 2015 Mar;21(2):133-41. doi: 10.1097/MCP.0000000000000145.
7
Genetic epidemiology of COPD (COPDGene) study design.COPD（COPDGene）遗传流行病学研究设计。
COPD. 2010 Feb;7(1):32-43. doi: 10.3109/15412550903499522.
8
The nature of small-airway obstruction in chronic obstructive pulmonary disease.慢性阻塞性肺疾病中小气道阻塞的本质。
N Engl J Med. 2004 Jun 24;350(26):2645-53. doi: 10.1056/NEJMoa032158.

Mucus plugging on computed tomography and chronic bronchitis in chronic obstructive pulmonary disease.

作者信息

Kim Victor, Dolliver Wojciech R, Nath Hrudaya P, Grumley Scott A, Terry Nina, Ahmed Asmaa, Yen Andrew, Jacobs Kathleen, Kligerman Seth, Diaz Alejandro A

机构信息

Lewis Katz School of Medicine at Temple University, 3401 North Broad Street, 785 Parkinson Pavilion, Philadelphia, PA, 19140, USA.

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.

出版信息

Respir Res. 2021 Apr 17;22(1):110. doi: 10.1186/s12931-021-01712-0.

DOI:10.1186/s12931-021-01712-0
PMID:33865371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8053272/
Abstract
摘要