Kim Victor, Criner Gerard J
Temple University School of Medicine, Philadelphia, Pennsylvania, USA.
Curr Opin Pulm Med. 2015 Mar;21(2):133-41. doi: 10.1097/MCP.0000000000000145.
Chronic obstructive pulmonary disease (COPD) is a major public health problem that is projected to rank fifth worldwide in terms of disease burden and third in terms of mortality. Chronic bronchitis is associated with multiple clinical consequences, including hastening lung function decline, increasing risk of exacerbations, reducing health-related quality of life, and possibly raising all-cause mortality. Recent data suggest greater elucidation on the risk factors, radiologic characteristics, and treatment regimens. Our goal was to review the literature on chronic bronchitis that has been published in the past few years.
A growing body of literature that more carefully describes environmental risk factors, epidemiology, and genetics associated with chronic bronchitis. In addition, as computed tomography technology continues to improve, the radiologic phenotype associated with chronic bronchitis is better understood.
With these new data, the clinician can recognize the newly described risk factors and the associated phenotype for chronic bronchitis and entertain new treatment options for this high-risk population.
慢性阻塞性肺疾病（COPD）是一个重大的公共卫生问题，预计在全球疾病负担方面排名第五，在死亡率方面排名第三。慢性支气管炎与多种临床后果相关，包括加速肺功能下降、增加急性加重风险、降低健康相关生活质量，并可能提高全因死亡率。近期数据表明，人们对其危险因素、放射学特征和治疗方案有了更深入的了解。我们的目标是回顾过去几年发表的关于慢性支气管炎的文献。
越来越多的文献更细致地描述了与慢性支气管炎相关的环境危险因素、流行病学和遗传学。此外，随着计算机断层扫描技术不断改进，与慢性支气管炎相关的放射学表型得到了更好的理解。
有了这些新数据，临床医生可以识别慢性支气管炎新描述的危险因素和相关表型，并为这一高危人群考虑新的治疗选择。
