Cambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Department of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.
Lancet Infect Dis. 2021 Jun;21(6):e170-e174. doi: 10.1016/S1473-3099(20)30835-5. Epub 2021 Apr 15.
Antimicrobial resistance (AMR) is a major threat to human health globally. Surveillance is a key activity to determine AMR burden, impacts, and trends and to monitor effects of interventions. Surveillance systems require efficient capture and onward sharing of high-quality laboratory data. Substantial investment is being made to improve laboratory capacity, particularly in low-income and middle-income countries (LMICs) with high disease burdens. However, building capacity for effective laboratory data management remains an under-resourced area, which, unless addressed, will limit progress towards comprehensive AMR surveillance in LMICs. The lack of a fit-for-purpose and open-source laboratory information management system software is of particular concern. In this Personal View, we summarise the technical requirements for microbiology laboratory data management, provide a snapshot of laboratory data management in LMIC laboratories, and describe the key steps required to improve the situation. Without action to improve information technology infrastructure and data management systems in microbiology laboratories, the ongoing efforts to develop capacity for AMR surveillance in LMICs might not realise their full potential.
抗菌药物耐药性（AMR）是全球范围内对人类健康的主要威胁。监测是确定 AMR 负担、影响和趋势以及监测干预措施效果的关键活动。监测系统需要高效地捕获和共享高质量的实验室数据。为了提高实验室能力，特别是在疾病负担高的低收入和中等收入国家（LMICs），正在进行大量投资。然而，建立有效的实验室数据管理能力仍然是一个资源不足的领域，如果不加以解决，将限制 LMICs 全面开展 AMR 监测的进展。缺乏用途广泛且开源的实验室信息管理系统软件尤其令人担忧。在这篇个人观点中，我们总结了微生物学实验室数据管理的技术要求，概述了 LMIC 实验室的实验室数据管理情况，并描述了改善这种情况所需的关键步骤。如果不采取行动改善微生物学实验室的信息技术基础设施和数据管理系统，那么在 LMICs 中开展 AMR 监测能力建设的持续努力可能无法充分发挥其潜力。
