鼠李糖乳杆菌 GR-1，又名罗伊氏乳杆菌 GR-1：过去与未来展望。
Lacticaseibacillus rhamnosus GR-1, a.k.a. Lactobacillus rhamnosus GR-1: Past and Future Perspectives.
机构信息
Microbiome Insights and Probiotics Consultancy, Karlovo, Bulgaria.
Canadian Research and Development Centre for Human Microbiome and Probiotics, Lawson Health Research Institute, London, Canada; Department of Microbiology and Immunology, The University of Western Ontario, London, Canada; Department of Surgery, The University of Western Ontario, London, Canada.
出版信息
Trends Microbiol. 2021 Aug;29(8):747-761. doi: 10.1016/j.tim.2021.03.010. Epub 2021 Apr 14.
Lacticaseibacillus rhamnosus GR-1 (LGR-1) (previously classified as Lactobacillus rhamnosus GR-1) is the most researched probiotic strain for women's health. Its various urogenital health effects, including a reduction in the recurrence of bacterial vaginosis and urinary-tract infection, are well documented. The strain has also been safely used by HIV-positive subjects, a portion of whom have reported reduced diarrhea and increased CD4 counts. Unlike most probiotic strains used for urogenital health, LGR-1 has been extensively studied for its properties, including its genomic and metabolic traits and its surface properties. This review aims to highlight the totality of research performed with LGR-1, to act as a rigorous scientific benchmark for probiotic microbes, especially for application to women's health.
鼠李糖乳杆菌 GR-1（以前被分类为鼠李糖乳杆菌 GR-1）是研究最多的用于女性健康的益生菌菌株。其对女性泌尿生殖健康的各种有益作用，包括降低细菌性阴道病和尿路感染的复发率，都有充分的文献记载。该菌株也已被 HIV 阳性患者安全使用，其中一部分患者报告腹泻减少和 CD4 计数增加。与用于泌尿生殖健康的大多数益生菌菌株不同，LGR-1 的特性，包括其基因组和代谢特性及其表面特性，已经得到了广泛的研究。本综述旨在强调对 LGR-1 进行的所有研究，为益生菌微生物，特别是在女性健康应用方面，提供一个严格的科学基准。
Zotero 插件