Kennedy Krieger Institute Neuropsychology Department.
Johns Hopkins School of Medicine Department of Psychiatry and Behavioral Sciences.
Child Neuropsychol. 2021 Oct;27(7):960-972. doi: 10.1080/09297049.2021.1917529. Epub 2021 Apr 18.
Sluggish Cognitive Tempo (SCT) describes a pattern of under-activity, poor initiation, and slowness. It was first reported within the Attention Deficit Hyperactivity Disorder (ADHD) literature and found to be positively associated with the inattentive symptoms of ADHD and negatively or not significantly associated with the hyperactivity/impulsivity symptoms of ADHD. SCT has since been considered applicable to the pediatric oncology population given the emergence of inattentive, sluggish symptoms secondary to cancer treatment. The present study examined the unique contribution of SCT to various processing speed skills in a clinical sample of pediatric brain tumor (BT) survivors in order to determine the degree to which SCT explained timed "cognitive" processing components. Measures included speeded naming, graphomotor speed, and speeded inhibition. Hierarchical linear regression analyses were used to predict performance-based measures of processing speed. After controlling for verbal ability and inattention, SCT, particularly Daydreamy SCT ( = -0.698, = 0.023), explained 28% of variance in speeded inhibition. SCT did not add significantly to the prediction of speeded naming or graphomotor speed. Findings suggest that the "daydreamy" aspect of SCT, rather than "sluggishness" per se, may be related to more complex, cognitively-demanding tasks with greater executive functioning burdens in BT survivors. Implications for intervention for oncology survivors as well as future research directions are discussed.
注意力障碍过动症(ADHD)描述了一种活动减少、注意力不集中和行动迟缓的模式。该模式最早在 ADHD 文献中报道,被发现与 ADHD 的注意力不集中症状呈正相关,与 ADHD 的多动/冲动症状呈负相关或不显著相关。此后,由于癌症治疗后出现注意力不集中、行动迟缓的症状,SCT 被认为适用于儿科肿瘤患者。本研究通过对儿科脑瘤(BT)幸存者的临床样本进行了 SCT 对各种加工速度技能的独特贡献,以确定 SCT 在多大程度上解释了定时“认知”加工成分。研究使用的测量方法包括快速命名、图形运动速度和快速抑制。采用分层线性回归分析预测基于表现的加工速度测量。在控制了言语能力和注意力不集中后,SCT(=-0.698,=0.023),尤其是白日梦样 SCT,解释了 28%的快速抑制的方差。SCT 对快速命名或图形运动速度的预测没有显著增加。研究结果表明,SCT 的“白日梦”方面,而不是单纯的“迟缓”,可能与 BT 幸存者更复杂、认知要求更高、执行功能负担更大的任务有关。本文讨论了对肿瘤学幸存者进行干预以及未来研究方向的意义。