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含可可碱牙膏对幼儿龋齿的防龋效果:初步结果

Caries Preventive Effects of Theobromine Containing Toothpaste on Early Childhood Caries: Preliminary Results.

作者信息

Durhan Muesser Ahu, Ozsalih Seda, Gokkaya Berna, Kulan Pinar Yildiz, Kargul Betul

机构信息

- Marmara University, Faculty of Dentistry, Department of Paediatric Dentistry, Istanbul, Turkey.

- Department of Paediatric Dentistry Bahcelievler Oral and Dental Health Hospital, Istanbul, Turkey.

出版信息

Acta Stomatol Croat. 2021 Mar;55(1):18-27. doi: 10.15644/asc55/1/3.

Abstract

OBJECTIVE

Enamel remineralizing effects of theobromine have received much attention from the clinicians. The aim of this study was to investigate the caries preventive effect of theobromine containing toothpaste on children with early childhood caries (ECC).

MATERIAL AND METHODS

Salivary pH, buffering capacity and frequency of (SM) levels were measured. Each child was assigned either fluoridated or theobromine containing toothpaste. The changes were analyzed using Laser Fluorescence system. Statistical analyses were performed.

RESULTS

We included 13 children (mean age 4.25) with 145 teeth in the fluoridated toothpaste (Colgate Kids toothpaste) group; 13 children (mean age 4.46) with 115 teeth in theobromine containing toothpaste (TheodentKids toothpaste) group. Both toothpastes demonstrated enamel remineralization and were effective in increasing the buffering capacity and pH (p < 0.05). A statistically significant decrease in levels was found in both toothpaste groups (p<0.05).

CONCLUSION

Both toothpaste group showed a statistically significant amount of enamel remineralization. Since theobromine had the added benefits of increasing the salivary pH and decreasing the levels, theobromine containing toothpastes can be considered effective agents in remineralizing white spot lesions and can be used in prevention of early enamel lesions.

摘要

目的

可可碱对牙釉质的再矿化作用已受到临床医生的广泛关注。本研究旨在探讨含可可碱牙膏对患有幼儿龋(ECC)儿童的防龋效果。

材料与方法

测量唾液pH值、缓冲能力和变形链球菌(SM)水平的频率。每个孩子被分配使用含氟牙膏或含可可碱牙膏。使用激光荧光系统分析变化情况,并进行统计分析。

结果

我们纳入了13名儿童(平均年龄4.25岁),含氟牙膏(高露洁儿童牙膏)组有145颗牙齿;13名儿童(平均年龄4.46岁),含可可碱牙膏(TheodentKids牙膏)组有115颗牙齿。两种牙膏均显示出牙釉质再矿化,且在提高缓冲能力和pH值方面有效(p < 0.05)。两个牙膏组的变形链球菌水平均有统计学显著下降(p<0.05)。

结论

两个牙膏组均显示出具有统计学意义的牙釉质再矿化量。由于可可碱具有提高唾液pH值和降低变形链球菌水平的额外益处,含可可碱牙膏可被视为使白斑病变再矿化的有效制剂,并可用于预防早期牙釉质病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9395/8033621/7de8bb20e8b4/ASC_55(1)_18-27-f1.jpg

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