进行性核上性麻痹的患病率及自然史。
Prevalence and natural history of progressive supranuclear palsy.
作者信息
Golbe L I, Davis P H, Schoenberg B S, Duvoisin R C
机构信息
Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, New Brunswick 08903.
出版信息
Neurology. 1988 Jul;38(7):1031-4. doi: 10.1212/wnl.38.7.1031.
We surveyed neurologists and chronic care facilities in and near two New Jersey counties with a combined population of 799,022, regarding cases of progressive supranuclear palsy. All suspected cases were examined personally, using rigid criteria. The prevalence ratio was 1.39/100,000. A total of 50 New Jersey cases yielded median intervals to onset of requiring gait assistance, 3.1 years; visual symptoms, 3.9 years; dysarthria, 3.4 years; dysphagia, 4.4 years; requiring wheelchair, 8.2 years; and death, 9.7 years.
我们对新泽西州两个县及其周边地区的神经科医生和慢性病护理机构进行了调查，这两个县的总人口为799,022人，调查内容为进行性核上性麻痹病例。所有疑似病例均依据严格标准进行了亲自检查。患病率为1.39/100,000。新泽西州的50例病例中，出现需要步态辅助症状的中位间隔时间为3.1年；出现视觉症状的为3.9年；构音障碍为3.4年；吞咽困难为4.4年；需要轮椅辅助的为8.2年；死亡为9.7年。
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