Singh Gurdeep, Irshaidat Fatima, Lau Christopher, Pedoeem Ariel, Feng Christine, Fariduddin Maria Mohammed, Min Lei Lei, Bansal Nidhi
Our Lady of Lourdes Memorial Hospital, 161 Riverside Drive, Binghamton 13905, NY, USA.
Upstate University Hospital, 3229 East Genesee Street, Syracuse 13214, NY, USA.
Int J Endocrinol. 2021 Apr 1;2021:5598319. doi: 10.1155/2021/5598319. eCollection 2021.
Post-thyroidectomy hypocalcemia is the most common complication after total thyroidectomy. Studies to examine the role of low vitamin D in increasing post-thyroidectomy hypocalcemia incidence have produced varying results. This study aimed to assess whether vitamin D deficiency increases the risk of post-thyroidectomy hypocalcemia.
This retrospective study involved 244 patients who underwent total thyroidectomy between 2014 and 2019. Patients were divided into two groups based on pre-operative vitamin D levels. Group A and Group B had pre-operative vitamin D (25-hydroxyvitamin D) levels of ≥20 ng/ml and <20 ng/ml (reference range for vitamin D is 30-100 ng/dl). The effect of vitamin D, gender, body mass index (BMI), and ethnicity on post-operative calcium and PTH levels was analyzed.
Post-operative calcium levels for Group A were not statistically different compared to Group B (8.52 ± 0.64 mg/dl vs. 8.45 ± 0.58 mg/dl (mean ± S.D.; value = 0.352). The average post-operative PTH of the two groups did not differ significantly (Group A: 32.4 ± 27.5 pg/ml; Group B: 34.4 ± 41.7 pg/ml; value = 0.761).
Pre-operative vitamin D levels are not predictive of post-thyroidectomy hypocalcemia.
甲状腺切除术后低钙血症是全甲状腺切除术后最常见的并发症。关于低维生素D在增加甲状腺切除术后低钙血症发生率中作用的研究结果不一。本研究旨在评估维生素D缺乏是否会增加甲状腺切除术后低钙血症的风险。
这项回顾性研究纳入了2014年至2019年间接受全甲状腺切除术的244例患者。根据术前维生素D水平将患者分为两组。A组和B组术前维生素D（25-羟维生素D）水平分别≥20 ng/ml和<20 ng/ml（维生素D的参考范围为30-100 ng/dl）。分析了维生素D、性别、体重指数（BMI）和种族对术后钙和甲状旁腺激素（PTH）水平的影响。
A组术后钙水平与B组相比无统计学差异（8.52±0.64 mg/dl vs. 8.45±0.58 mg/dl（均值±标准差；P值=0.352）。两组术后平均PTH无显著差异（A组：32.4±27.5 pg/ml；B组：34.4±41.7 pg/ml；P值=0.761）。
术前维生素D水平不能预测甲状腺切除术后低钙血症。
