Holick Michael F
Endocrinology, Nutrition and Diabetes, Department of Medicine, Boston University Medical Center, Boston, MA, 02118, USA.
Rev Endocr Metab Disord. 2017 Jun;18(2):153-165. doi: 10.1007/s11154-017-9424-1.
Vitamin D deficiency and insufficiency is a global health issue that afflicts more than one billion children and adults worldwide. The consequences of vitamin D deficiency cannot be under estimated. There has been an association of vitamin D deficiency with a myriad of acute and chronic illnesses including preeclampsia, childhood dental caries, periodontitis, autoimmune disorders, infectious diseases, cardiovascular disease, deadly cancers, type 2 diabetes and neurological disorders. This review is to put into perspective the controversy surrounding the definition for vitamin D deficiency and insufficiency as well as providing guidance for how to treat and prevent vitamin D deficiency.
维生素D缺乏和不足是一个全球性的健康问题，困扰着全球超过10亿儿童和成人。维生素D缺乏的后果不容小觑。维生素D缺乏与众多急慢性疾病有关，包括先兆子痫、儿童龋齿、牙周炎、自身免疫性疾病、传染病、心血管疾病、致命癌症、2型糖尿病和神经系统疾病。这篇综述旨在正确看待围绕维生素D缺乏和不足定义的争议，并为如何治疗和预防维生素D缺乏提供指导。
