Department of Psychiatry, Chang Gung Memorial Hospital at Linkou, 333 Taoyuan, Taiwan.
School of Medicine, Chang Gung University, 333 Taoyuan, Taiwan.
Behav Neurol. 2021 Apr 1;2021:8880539. doi: 10.1155/2021/8880539. eCollection 2021.
To describe a case of lung cancer with brain metastasis in a patient who developed new late-onset bipolar disorder 2 years previously.
The typical onset age of bipolar disorder is approximately 20, and the first episode is usually a depressive episode. It is still not clear which age-specific factors contribute to the underlying risk.
A 65-year-old male patient presented with a new-onset manic episode characterized by labile mood, impulsivity, decreased need for sleep, and grandiosity. He was diagnosed with late-onset bipolar disorder after excluding other possible physiological conditions. He was hospitalized in the acute psychiatric ward, and a combination of mood stabilizers and antipsychotics was prescribed. His mental condition improved, and he remained stable for 2 years. However, he experienced abrupt cognitive decline for 2 months and was referred to the emergency room for physiological examination.
The patient was diagnosed with lung cancer with brain metastasis by brain magnetic resonance imaging and whole-body positron emission tomography.
In geriatric patients, who are at high risk of multiple medical conditions, excluding secondary causes of bipolar disorder is important.
描述一例肺癌伴脑转移患者，该患者 2 年前新发迟发性双相障碍。
双相障碍的典型发病年龄约为 20 岁，首发通常为抑郁发作。目前尚不清楚哪些特定年龄的因素导致了潜在风险。
一名 65 岁男性患者出现新发躁狂发作，表现为情绪波动、冲动、睡眠需求减少和夸大妄想。在排除其他可能的生理状况后，他被诊断为迟发性双相障碍。他被收入急性精神科病房，给予心境稳定剂和抗精神病药联合治疗。他的精神状况改善，2 年来一直保持稳定。然而，他在 2 个月前突然出现认知能力下降，并被转至急诊室进行生理检查。
脑部磁共振成像和全身正电子发射断层扫描显示患者患有肺癌伴脑转移。
在易患多种疾病的老年患者中，排除双相障碍的继发性病因很重要。
