Subramoniam Madhusoodanan, Department of Psychiatry, St. John's Episcopal Hospital, Far Rockaway, NY 11691, United States.
World J Psychiatry. 2015 Sep 22;5(3):273-85. doi: 10.5498/wjp.v5.i3.273.
Infrequently, psychiatric symptoms may be the only manifestation of brain tumors. They may present with mood symptoms, psychosis, memory problems, personality changes, anxiety, or anorexia. Symptoms may be misleading, complicating the clinical picture. A comprehensive review of the literature was conducted regarding reports of brain tumors and psychiatric symptoms from 1956-2014. Search engines used include PubMed, Ovid, Psych Info, MEDLINE, and MedScape. Search terms included psychiatric manifestations/symptoms, brain tumors/neoplasms. Our literature search yielded case reports, case studies, and case series. There are no double blind studies except for post-diagnosis/-surgery studies. Early diagnosis is critical for improved quality of life. Symptoms that suggest work-up with neuroimaging include: new-onset psychosis, mood/memory symptoms, occurrence of new or atypical symptoms, personality changes, and anorexia without body dysmorphic symptoms. This article reviews the existing literature regarding the diagnosis and management of this clinically complex condition.
偶尔,精神症状可能是脑瘤的唯一表现。它们可能表现为情绪症状、精神病、记忆问题、人格改变、焦虑或厌食。症状可能具有误导性,使临床表现复杂化。对 1956 年至 2014 年有关脑瘤和精神症状的报告进行了文献综述。使用的搜索引擎包括 PubMed、Ovid、Psych Info、MEDLINE 和 MedScape。搜索词包括精神表现/症状、脑肿瘤/肿瘤。我们的文献检索结果包括病例报告、病例研究和病例系列。除了诊断后/手术后研究外,没有双盲研究。早期诊断对于提高生活质量至关重要。需要进行神经影像学检查的症状包括:新发精神病、情绪/记忆症状、出现新的或非典型症状、人格改变和无体变形症状的厌食。本文综述了现有文献中关于这种临床复杂情况的诊断和治疗。