Scott Jessica M, Downs Meghan, Martin David S, Hougland Erik, Sarmiento Laura, Arzeno Natalia, Pettit Donald R, Ploutz-Snyder Robert, Cunningham David, Jones Lee W, Do Richard, Ploutz-Snyder Lori
Department of Medicine, Memorial Sloan Kettering Cancer Center, 485 Lexington Avenue, New York, NY 10017, USA.
Weill Cornell Medical College, New York, NY 10017, USA.
iScience. 2021 Mar 21;24(4):102344. doi: 10.1016/j.isci.2021.102344. eCollection 2021 Apr 23.
Loss of muscle mass is a major concern for long duration spaceflight. However, due to the need for specialized equipment, muscle size has only been assessed before and after spaceflight where ~20% loss is observed. Here, we demonstrate the utility of teleguided self-ultrasound scanning (Tele-SUS) to accurately monitor leg muscle size in astronauts during spaceflight. Over an average of 168 ± 57 days of spaceflight, 74 Tele-SUS sessions were performed. There were no significant differences between panoramic ultrasound images obtained by astronauts seven days prior to landing and expert sonographer after flight or between change in muscle size assessed by ultrasound and magnetic resonance imaging. These findings extend the current capabilities of ultrasound imaging to allow self-monitoring of muscle size with remote guidance.
肌肉质量的流失是长期太空飞行的一个主要问题。然而，由于需要专门设备，肌肉大小仅在太空飞行前后进行了评估，观察到约20%的流失。在此，我们展示了远程引导的自我超声扫描（Tele-SUS）在太空飞行期间准确监测宇航员腿部肌肉大小的实用性。在平均168±57天的太空飞行期间，进行了74次Tele-SUS检查。宇航员着陆前七天获得的全景超声图像与飞行后专家超声检查人员获得的图像之间，以及通过超声和磁共振成像评估的肌肉大小变化之间，均无显著差异。这些发现扩展了超声成像的当前能力，以实现远程引导下的肌肉大小自我监测。
