Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana, USA.
Vet Rec. 2021 May;188(9):e299. doi: 10.1002/vetr.299. Epub 2021 Apr 19.
The Dogo Argentino dog breed is affected by hereditary congenital sensorineural deafness (CSD) associated with white pigmentation, but prevalence data and associations with phenotypes have not been reported.
In a retrospective study, animals were tested by the brainstem auditory evoked response, and phenotype data of sex, iris color, patch presence/absence and parent hearing status were collected. Chi-square analyses were performed to identify associations between deafness and phenotype traits.
BAER results and phenotype data were collected for 811 dogs. Hearing status was 74.23% bilaterally hearing, 20.35% unilaterally deaf and 5.43% bilaterally deaf or an overall prevalence of 25.77%. CSD was not associated with sex, but dogs without a patch had a significantly higher prevalence rate than patched dogs. Blue-eyed dogs had higher prevalence rates than brown-eyed dogs, but because of small sample size the χ association was not considered valid. Insufficient numbers of dogs with a unilaterally deaf parent were present to assess the effects of parent hearing status.
Approximately one fourth of a US Dogo Argentino population was deaf in one or both ears, but dogs with a patch had a lower prevalence. Dogs with a blue eye were more likely to be deaf, but the association significance could not be reliably assessed.
阿根廷杜高犬种受遗传性先天性感觉神经性耳聋（CSD）的影响，与白色色素沉着有关，但尚未报道其流行率数据和与表型的关联。
在一项回顾性研究中，通过脑干听觉诱发电位对动物进行测试，并收集了性别、虹膜颜色、斑块存在/缺失和父母听力状况的表型数据。进行卡方分析以确定耳聋与表型特征之间的关联。
共收集了 811 只狗的 BAER 结果和表型数据。听力状况为双侧听力 74.23%，单侧耳聋 20.35%，双侧耳聋或总患病率为 25.77%。CSD 与性别无关，但无斑块的狗的患病率明显高于有斑块的狗。蓝眼睛的狗比棕色眼睛的狗有更高的患病率，但由于样本量小，χ 关联被认为无效。单侧耳聋父母的狗数量不足，无法评估父母听力状况的影响。
约四分之一的美国杜高犬种群在一只或两只耳朵失聪，但有斑块的狗患病率较低。蓝眼睛的狗更有可能耳聋，但关联意义无法可靠评估。
