Department of Internal Medicine, Erzurum Regional Training and Research Hospital, Health Sciences University, Erzurum, Turkey.
Acta Clin Belg. 2022 Jun;77(3):588-595. doi: 10.1080/17843286.2021.1916687. Epub 2021 Apr 17.
Associations of depression, dementia, and poor life quality with mortality of COVID-19have not been studied yet. We aimed to identify the risk factors for mortality and analyze the associations with patients' physiological and mental well-being, as reflected by comorbidities, life quality, depression, and cognitive impairment.
: Older patients receiving inpatient hospital care for COVID-19 were included.Demographic data, medical history, symptoms at admission, laboratory findings, and treatment outcomes were recorded.
: There were 122 patients with a median age of 73.0 years. The mortality rate was 9.0% (n = 11 patients). Patients with mortality were significantly active smokers, obese, and having comorbidities using polypharmacy. Weight loss ≥of 10% during hospitalization was significantly associated with mortality.Poor life quality and a higher risk of depression, cognitive impairment, and falling were more frequently seen in non-survived patients. (p < 0.05). High ferritin was the only independent risk factor for mortality (OR = 15.61, 95% CI:1.08-226.09, p = 0.044).
: The presence of comorbidities, depression, cognitive impairment, higher falling risk, and poor life quality were significantly associated with higher mortality rates in older adults with COVID-19. High ferritin level was an independent risk factor for mortality.
尚未研究抑郁、痴呆和生活质量差与 COVID-19 死亡率之间的关系。我们旨在确定死亡率的危险因素，并通过合并症、生活质量、抑郁和认知障碍来分析与患者生理和心理健康相关的因素。
纳入因 COVID-19 接受住院治疗的老年患者。记录人口统计学数据、病史、入院时的症状、实验室检查结果和治疗结果。
共有 122 名中位年龄为 73.0 岁的患者。死亡率为 9.0%（n=11 例）。有死亡的患者明显是活跃的吸烟者、肥胖者，且合并症使用了多种药物治疗。住院期间体重减轻≥10%与死亡率显著相关。非存活患者的生活质量较差，且抑郁、认知障碍和跌倒的风险更高（p<0.05）。高铁蛋白是死亡率的唯一独立危险因素（OR=15.61，95%CI：1.08-226.09，p=0.044）。
合并症、抑郁、认知障碍、更高的跌倒风险和较差的生活质量与 COVID-19 老年患者的高死亡率显著相关。高铁蛋白水平是死亡率的独立危险因素。
