Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Department of Chemistry, Institute of Molecular Aggregation Science, Tianjin University, Tianjin 300072, China.
Chem Soc Rev. 2021 May 7;50(9):5366-5396. doi: 10.1039/d0cs01538e. Epub 2021 Apr 19.
Selective organic transformations using metal-organic frameworks (MOFs) and MOF-based heterogeneous catalysts have been an intriguing but challenging research topic in both the chemistry and materials communities. Analogous to the reaction specificity achieved in enzyme pockets, MOFs are also powerful platforms for regulating the catalytic selectivity via engineering their catalytic microenvironments, such as metal node alternation, ligand functionalization, pore decoration, topology variation and others. In this review, we provide a comprehensive introduction and discussion about the role of MOFs played in regulating and even boosting the size-, shape-, chemo-, regio- and more appealing stereo-selectivity in organic transformations. We hope that it will be instructive for researchers in this field to rationally design, conveniently prepare and elaborately functionalize MOFs or MOF-based composites for the synthesis of high value-added organic chemicals with significantly improved selectivity.
使用金属-有机骨架（MOFs）和基于 MOF 的多相催化剂进行选择性有机转化，是化学和材料领域中一个令人感兴趣但极具挑战性的研究课题。与酶口袋中实现的反应特异性类似，MOFs 也是通过工程化其催化微环境来调节催化选择性的有力平台，例如改变金属节点、配体功能化、孔道修饰、拓扑结构变化等。在这篇综述中，我们全面介绍和讨论了 MOFs 在调节甚至增强有机转化中尺寸、形状、化学、区域和更吸引人的立体选择性方面的作用。我们希望这将对该领域的研究人员有所启发，以便合理设计、方便制备和精细功能化 MOFs 或基于 MOF 的复合材料，用于合成具有显著改善选择性的高附加值有机化学品。
