School of Medicine, National Yang Ming Chiao Tung University, Hsinchu, Taiwan, ROC.
School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2021 Jul 1;84(7):733-735. doi: 10.1097/JCMA.0000000000000525.
Uremic pericarditis and pericardial effusion are possible complications among patients with end-stage renal disease. The accumulation of toxic metabolites may contribute to the pathogenesis of uremic pericarditis. Bleeding diathesis in peritoneal dialysis patients raises the risk of hemorrhagic pericardial tamponade, which is a fatal complication of peritoneal dialysis. We report a case of hemorrhagic pericardial tamponade who was nonadherent to peritoneal dialysis with initial presentation of hypotension and syncope. Transthoracic echocardiogram revealed septated, fibrinoid pericardial effusion and right ventricular diastolic compression. A massive bloody pericardial effusion was drained when he underwent the pericardial window procedure. There was a significant improvement both in his clinical condition and in the echocardiogram images after the procedure. Hemorrhagic pericardial tamponade occurs in uremic patients but is rarely seen in those undergoing peritoneal dialysis. Early diagnosis, immediate surgical drainage, and regular follow-up with echocardiography are crucial to achieve better prognoses in future similar clinical scenarios.
尿毒症性心包炎和心包积液是终末期肾病患者可能出现的并发症。毒性代谢产物的积累可能导致尿毒症性心包炎的发病机制。腹膜透析患者的出血倾向增加了出血性心包填塞的风险,这是腹膜透析的致命并发症。我们报告了一例因不遵医嘱进行腹膜透析而导致出血性心包填塞的病例,该患者最初表现为低血压和晕厥。经胸超声心动图显示分隔的纤维蛋白性心包积液和右心室舒张期受压。心包开窗术时引流出大量血性心包积液。术后患者的临床状况和超声心动图图像均有显著改善。尿毒症患者可发生血性心包填塞,但在腹膜透析患者中很少见。早期诊断、立即手术引流以及定期随诊行超声心动图检查对于未来类似临床情况下获得更好的预后至关重要。